Synthesis of Aziridines and Oxaziridines from Imines

Aziridines and oxaziridines are synthesized from imines, a rapidly growing branch of heterocyclic chemistry with important advances in recent years. They have numerous pharmaceutical and organic synthesis applications, including antitumor agents, enzyme inhibitors, and antibiotics. Despite their reactivity, aziridines are found in many synthetic compounds and natural products.

Format: Paperback / softback
Length: 352 pages
Publication date: 17 January 2024
Publisher: Elsevier - Health Sciences Division

Synthesis of Aziridines and Oxaziridines from Imines is a comprehensive guide to the synthesis of aziridines and oxaziridines from imines, covering both new and old methods. It is an important and rapidly growing branch of heterocyclic chemistry, with numerous advances in recent years. Aziridines are well-known for their potential in pharmaceutical chemistry and organic synthesis, with the smallest possible saturated azaheterocycle, aziridine, being highly reactive. They have found numerous uses as subunits in pharmacologically active compounds, including antitumor agents, enzyme inhibitors, and antibiotics. Despite their reactivity, aziridines are present in many synthetic compounds and natural products of biological interest. The book provides readers with access to different methods and information, allowing them to evaluate which method is most suitable for particular cases.

Weight: 740g
Dimension: 191 x 233 x 20 (mm)
ISBN-13: 9780443220593