Synthetic Strategies in Carbohydrate Chemistry

Synthetic Strategies in Carbohydrate Chemistry is a comprehensive reference that covers carbohydrate synthesis and its widespread application in various disciplines, including catalysis. It discusses recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides, and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification. It also highlights diverse applications of synthetic carbohydrate chemistry, such as sugar-based chiral catalysts, sugar-based ionic liquids, one-pot tandem reactions, total synthesis of glycoconjugated natural products, vaccine development, and glycoengineering.

Format: Paperback / softback
Length: 650 pages
Publication date: 01 October 2023
Publisher: Elsevier - Health Sciences Division

Synthetic Strategies in Carbohydrate Chemistry delves into the realm of carbohydrate synthesis, exploring its extensive applications across various disciplines, including catalysis. It encompasses both fundamental and advanced aspects of carbohydrates, commencing with a concise introduction before delving into protection-deprotection strategies, glycosidic bond formation methodologies, and their profound impact on oligosaccharide synthesis. The text also discusses recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides, and C-glycosides, as well as Intramolecular Aglycon Delivery (IAD), and carbohydrate modification. Furthermore, it explores stereoelectronic factors that govern the chemical and biochemical behavior of carbohydrates within living cells. Additionally, the book covers diverse applications of synthetic carbohydrate chemistry, such as the utilization of sugar-based chiral catalysts in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, the significance of sugar in drug discovery and development, vaccine development, and glycoengineering. This comprehensive reference serves as an indispensable resource for researchers engaged in synthetic carbohydrate chemistry and biochemistry, as well as those involved in total synthesis, novel synthetic methodologies, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry.

Dimension: 229 x 152 (mm)
ISBN-13: 9780323917292