Systems Medicine

This book explores the latest technological advances in systems medicine and precision medicine, including proteomics, computational approaches, network biology, toxicology, and modeling. It is written in the Methods in Molecular Biology series format and is a valuable resource for researchers.

Format: Paperback / softback
Length: 347 pages
Publication date: 20 April 2023
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into the most recent technological advancements and provides a comprehensive exploration of systems medicine, particularly in the context of precision medicine. The book is organized into four distinct parts, each addressing key aspects of this field.

Part One focuses on the recent achievements in proteomics, highlighting the identification of biomarkers, the integration of omics and phenotypic data for precision medicine, and the application of medicine-guided treatment for drug-induced Stevens-Johnson syndrome.

Part Two delves into systems-based computational approaches for pharmaceutical research and drug development. It covers topics such as optimizing systemic exposure of drugs, the principle of Animal Rule for drug repurposing, and computational tools and methodologies of network biology, quantitative systems toxicology, and modeling and stimulating patient response variabilities.

Part Three explores computational tools and methodologies of network biology, quantitative systems toxicology, and modeling and stimulating patient response variabilities. It provides detailed insights into the development of computational models and their applications in understanding complex biological systems and predicting patient outcomes.

Part Four examines how systems medicine can address unmet medical and health needs and identify educational needs. It discusses the potential applications of systems medicine in personalized medicine, drug discovery, and disease management.

Written in the highly successful Methods in Molecular Biology series format, the chapters in this book include comprehensive introductions to their respective topics, detailed lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and helpful tips on troubleshooting and avoiding known pitfalls.

With its cutting-edge and thorough coverage, Systems Medicine: Methods and Protocols serves as a valuable resource for the scientific community. It will facilitate collaboration among researchers in advancing the goal of promoting global health and advancing the field of systems medicine.

Chapter 8 is available open access under a Creative Commons Attribution 4.0 International License via the following link: link.springer.com.

Weight: 692g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071622674
Edition number: 1st ed. 2022