Textbook of Drug Design and Discovery

The Textbook of Drug Design and Discovery,Fifth Edition,is a comprehensive and up-to-date resource for students of chemistry,pharmacy,pharmacology,biochemistry,and medicine. It covers molecular recognition, ligand-based drug design, biostructure-based drug design, drug-like properties, decision-making in medicinal chemistry, chemical biology, natural products, in vivo imaging, peptide and protein drug design, prodrugs, enzyme inhibitors, receptors, ion channels, neurotransmitter transporters, important neurotransmitter systems, GABA and glutamic acid receptors, acetylcholine, histamine, dopamine, serotonin, opioid, and cannabinoid receptors, and neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.

Format: Paperback / softback
Length: 452 pages
Publication date: 13 June 2022
Publisher: Taylor & Francis Ltd

The Fifth Edition of the Textbook of Drug Design and Discovery, a comprehensive resource for students studying chemistry, pharmacy, pharmacology, biochemistry, and medicine, has been extensively revised and updated to offer a thorough understanding of all aspects of drug design and discovery. This edition builds upon the success of its predecessors and presents the information in a timely and educational manner.

The textbook begins with an introduction to drug design and discovery, providing an overview of the fundamental concepts and methodologies involved. The first eight chapters delve into molecular recognition, ligand-based drug design, and biostructure-based drug design, covering key topics such as ligand binding, receptor interactions, and drug design strategies.

The authors then explore drug-like properties and decision-making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery. The middle six chapters provide a comprehensive overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors discuss the structure, function, and pharmacology of receptors, ion channels, and neurotransmitter transporters, highlighting their importance in drug discovery and development.

The subsequent chapters focus on important neurotransmitter systems, including GABA and glutamic acid receptors, acetylcholine, histamine, dopamine, and serotonin, as well as opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics, providing valuable insights into these areas of drug research and development.

Throughout the textbook, the information is presented in an up-to-date review format, with an underlying focus on educational aspects. The authors have included numerous examples, figures, and tables to illustrate key concepts and facilitate understanding. Additionally, the textbook includes a comprehensive glossary and an extensive bibliography to provide further resources for students seeking to explore these topics in greater depth.

The Fifth Edition of the Textbook of Drug Design and Discovery is an invaluable resource for students, researchers, and professionals in the field of drug design and discovery. Its comprehensive coverage of all aspects of drug design and discovery, coupled with its educational approach, makes it an essential tool for anyone seeking to advance their knowledge in this field.

Dimension: 254 x 178 (mm)
ISBN-13: 9781032339948
Edition number: 5 ed