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Textbook of Von Willebrand Disease: Basic and Clinical Aspects

Textbook of Von Willebrand Disease: Basic and Clinical Aspects

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  • More about Textbook of Von Willebrand Disease: Basic and Clinical Aspects


The second edition of Textbook of von Willebrand Disease: Basic and Clinical Aspects provides comprehensive coverage of the latest research on von Willebrand disease, including its molecular biology, genetic variants, obstetric and gynecological manifestations, and management for surgery. It is edited by a team of experts and is a valuable resource for hematologists, thrombosis specialists, and bleeding/clotting disorders specialists.

Format: Hardback
Length: 304 pages
Publication date: 25 April 2024
Publisher: John Wiley and Sons Ltd


The second edition of Textbook of von Willebrand Disease: Basic and Clinical Aspects, a comprehensive resource summarizing recent research on von Willebrand disease, is now available. This revised and updated edition provides clinicians with valuable insights into optimizing the management of patients with this disorder.

The book delves into the intricate role of von Willebrand factor (VWF) in hemostasis and thrombosis, encompassing not only the current understanding of its molecular biology but also the association between genetic variants of VWF and various von Willebrand disease (VWD) phenotypes. It also explores the significant area of obstetric and gynecological manifestations of VWD, offering guidance on managing patients with VWD for surgery.

In this updated edition, numerous advances in agents and wide-ranging topics such as VWF in angiogenesis and VWF/ADAMTS13 as risk factors of thrombosis are included. The textbook is edited by a team of experts in VWD and an international team of contributors, covering a range of sample topics such as:

VWF structure and function, biosynthesis and organization of VWF, modulation of VWF by ADAMTS13, and assessment of VWF clearance.

Clinical, laboratory, and molecular markers of different VWD types, ranging from the mild forms of type 1 VWD to the moderate variants types 2A, 2B, 2M, 2N, and the most severe type 3 VWD.

Pediatric aspects of VWD and the impact on women with VWD.

Management of gastrointestinal bleeds and appropriate therapies in surgery, as well as plasma-derived and recombinant VWF concentrates.

Acquired von Willebrand Syndrome, cardiovascular causes of AVWS, gastrointestinal bleeds in VWD and AVWS, and prophylaxis in von Willebrand disease.

Providing comprehensive and accessible coverage of the subject, Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2nd. Edition is an invaluable resource for healthcare professionals seeking to enhance their understanding and treatment of VWD.

Weight: 1006g
Dimension: 221 x 283 x 24 (mm)
ISBN-13: 9781119419488
Edition number: 2 ed

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