Therapeutic potential of Cell Cycle Kinases in Breast Cancer

This book explores the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints, and dysregulation in breast cancer, and their prognostic significance. It also discusses CDK inhibitors for the treatment of metastatic breast cancer and the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation. It examines the immunogenic effects of CDK inhibitors, the mechanism of resistance, and current clinical trials in breast cancer treatment. Finally, it explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer.

Format: Hardback
Length: 373 pages
Publication date: 04 March 2023
Publisher: Springer Verlag, Singapore

This captivating book delves into the intricate relationship between cell cycle regulators and breast cancer phenotypes, providing a comprehensive review of the roles played by Cyclin-Dependent Kinases (CDKs) in driving cell cycle progression, cell cycle checkpoints, and dysregulation in breast cancer. It also explores the prognostic significance of CDKs in predicting the outcome of breast cancer patients. Furthermore, the book discusses the potential of CDK inhibitors as a treatment option for metastatic breast cancer, highlighting their effectiveness in inhibiting CDK activity and suppressing tumor growth.

In addition to exploring CDK inhibitors, the book delves into the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. It examines the immunogenic effects of CDK inhibitors and explores the mechanisms of resistance to these therapies. The book also provides an overview of current clinical trials in breast cancer treatment, shedding light on the latest advancements and breakthroughs in this field.

Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. It highlights the potential of targeting specific cell cycle stages or molecules to develop more effective and personalized treatments for breast cancer patients.

This book serves as a valuable resource for oncologists and researchers seeking to understand the therapeutic potential of Cyclin-Dependent Kinases in breast cancer. It provides a comprehensive yet concise overview of the latest research and developments in this field, making it an essential read for anyone interested in exploring the latest advancements in breast cancer treatment.

Weight: 752g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811989100
Edition number: 1st ed. 2023