Tissue Barriers in Disease, Injury and Regeneration

Tissue Barriers in Disease, Injury, and Regeneration explores the molecular and cellular fundamentals of homeostatic and defense responses, emphasizing the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid, and reticuloendothelial cells. It also covers the remodeling and regeneration of tissue stroma, vasculature, and progenitor cells.

Format: Paperback / softback
Length: 206 pages
Publication date: 23 June 2021
Publisher: Elsevier Science Publishing Co Inc

Tissue Barriers in Disease, Injury, and Regeneration delves into the intricate molecular and cellular underpinnings of homeostatic and defensive responses within tissue barriers. This comprehensive text explores the detrimental effects and exposure to pathogens and engineered nanomaterials. It emphasizes the crucial role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid, and reticuloendothelial cells, as well as the interplay between their actions and the influence of environmental factors, medical treatments, drug delivery systems, and alterations in barrier integrity, tissue/organ functions, and metabolic status. Furthermore, it delves into the regenerative potential of progenitor cells from diverse origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and other vital aspects of tissue repair and healing. By providing a deep understanding of these complex processes, Tissue Barriers in Disease, Injury, and Regeneration serves as a valuable resource for researchers, medical professionals, and students in the fields of medicine, biology, and biotechnology.

Tissue Barriers in Disease, Injury, and Regeneration is a comprehensive text that delves into the intricate molecular and cellular underpinnings of homeostatic and defensive responses within tissue barriers. This text explores the detrimental effects and exposure to pathogens and engineered nanomaterials, emphasizing the crucial role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid, and reticuloendothelial cells. It also highlights the interplay between their actions and the influence of environmental factors, medical treatments, drug delivery systems, and alterations in barrier integrity, tissue/organ functions, and metabolic status. Furthermore, the text delves into the regenerative potential of progenitor cells from diverse origins in the remodeling and regeneration of tissue stroma, the vasculature of blood-tissue barriers, and other vital aspects of tissue repair and healing.

The book is organized into several sections, each focusing on a specific aspect of tissue barriers. The first section provides an overview of the molecular and cellular fundamentals of tissue barriers, including their structure, function, and regulation. It also discusses the damaging impacts of pathogens and engineered nanomaterials on tissue barriers and the mechanisms by which they elicit immune responses.

The second section explores the role of mesenchymal stoma, vascular, epithelial, telocyte, myofibroblast, lymphoid, and reticuloendothelial cells in the defense and repair of tissue barriers. It discusses their interactions, signaling pathways, and contributions to maintaining barrier integrity and promoting tissue regeneration. The third section focuses on the reactions that bridge the effects of ambient factors, medical treatments, drug delivery systems, and alterations in barrier integrity on tissue/organ functions and metabolic status. It discusses the role of these reactions in the development of diseases such as cancer, inflammation, and autoimmune disorders.

The fourth section covers the role of progenitor cells of different origins in the remodeling and regeneration of tissue stroma, vasculature of blood-tissue barriers, and other vital aspects of tissue repair and healing. It discusses the mechanisms by which these cells contribute to tissue repair, including their differentiation, proliferation, and integration into the existing tissue structure.

The fifth section explores the use of engineered nanomaterials and their potential impact on tissue barriers. It discusses the advantages and disadvantages of using these materials in medical applications, including their ability to enhance drug delivery, promote tissue regeneration, and target specific cells or tissues. It also highlights the potential risks and challenges associated with their use, such as toxicity, immune responses, and unintended consequences.

In conclusion, Tissue Barriers in Disease, Injury, and Regeneration is a valuable resource for researchers, medical professionals, and students in the fields of medicine, biology, and biotechnology. It provides a comprehensive understanding of the molecular and cellular fundamentals of tissue barriers, their role in defense and repair, and their interactions with environmental factors, medical treatments, and drug delivery systems. The text also explores the regenerative potential of progenitor cells and the use of engineered nanomaterials in tissue repair and healing. By providing a deep understanding of these complex processes, Tissue Barriers in Disease, Injury, and Regeneration serves as a foundation for future research and innovation in the field.

Weight: 348g
Dimension: 152 x 229 x 17 (mm)
ISBN-13: 9780128185612