Transcriptomics from Aquatic Organisms to Humans

Next-generation sequencing and RNA-seq are used to measure gene expression in response to stimuli, generating transcriptional profiles from humans, fish, and crustaceans. This book covers transcriptomic studies of non-infectious and infectious diseases, as well as environmental and physiological correlates in shrimp and fish aquaculture. It is intended for undergraduate and graduate students interested in transcriptomics and its applications in various research areas.

Format: Paperback / softback
Length: 182 pages
Publication date: 29 January 2024
Publisher: Taylor & Francis Ltd

Next-generation sequencing (NGS) and RNA-seq are powerful molecular techniques that have revolutionized our ability to measure gene expression in response to various stimuli. These techniques provide highly accurate and sensitive data, allowing researchers to generate transcriptional profiles from a wide range of species, including humans, fish, and crustaceans.

In this comprehensive book, experts in the field present transcriptomic studies of non-infectious and infectious diseases affecting humans, as well as environmental and physiological correlates affecting shrimp and fish aquaculture. The book is designed for undergraduate and graduate students interested in exploring the diverse research areas transformed by transcriptomics, such as human disease, fish and crustacean physiology, environmental issues, and farming practices.

One of the key features of this book is its documentation of the utility of NGS and RNA-seq in addressing a wide array of aquatic environmental and physiological issues. The authors showcase how transcriptomics can contribute to our understanding of aquatic animal behavior, fish ecology, and the impact of environmental factors on aquatic ecosystems. They also discuss the application of transcriptomics in human health, where it has been used to identify novel biomarkers, diagnose diseases, and develop personalized treatments.

Another important aspect of the book is its exploration of the evolution of the techniques used to determine the transcriptome in crustacean aquaculture. The authors provide detailed insights into the methods and technologies employed, including single-cell RNA-seq, droplet-based sequencing, and microarray analysis. They discuss the challenges and opportunities associated with these techniques and their potential applications in improving crustacean aquaculture productivity and sustainability.

Furthermore, the book delves into the mechanisms of genetic interactions between different pathogens and the human host, and their effects on modifying gene expression levels. The authors discuss the role of transcriptomics in understanding the pathogenesis of infectious diseases, such as COVID-19, and the development of vaccines and therapeutics. They also explore the use of transcriptomics in personalized medicine, where it can be used to identify genetic variations that contribute to disease risk and develop targeted treatments.

In conclusion, this book is a valuable resource for researchers, students, and practitioners interested in transcriptomics and its applications in aquatic environments, human health, and other research areas. It provides a comprehensive overview of the latest techniques, methodologies, and applications, and serves as a roadmap for future research and innovation in this field.

Weight: 453g
Dimension: 234 x 156 (mm)
ISBN-13: 9781032079943