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A.J. Larner

Transient Global Amnesia: From Patient Encounter to Clinical Neuroscience

Transient Global Amnesia: From Patient Encounter to Clinical Neuroscience

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  • More about Transient Global Amnesia: From Patient Encounter to Clinical Neuroscience


A comprehensive overview of transient global amnesia (TGA) is provided in this second edition, covering its history, clinical features, diagnostic criteria, investigation, and pathogenesis. It is designed for clinicians from various medical backgrounds and uses case studies to illustrate the material.

Format: Paperback / softback
Length: 179 pages
Publication date: 12 June 2023
Publisher: Springer Nature Switzerland AG


This extensively revised second edition provides a comprehensive overview of transient global amnesia (TGA). First, it deals with the history of TGA before moving on to clinical and diagnostic features and differential diagnosis. Subsequent chapters then discuss the investigation and predisposing and precipitating factors for TGA before attempting to synthesise these many strands in order to formulate ideas about the pathogenesis of TGA. Each of the chapters is devoted to a practical and structured overview of the particular topic, with use of case studies to illustrate the material. Based in part on the authors experience of TGA cases over 20 years and in part on a review of the published literature, this book will hopefully enlighten clinicians from a broad range of medical backgrounds on the clinical features, investigation, and pathogenesis of TGA.

Transient Global Amnesia (TGA) is a fascinating neurological condition that has garnered significant attention in the medical literature. This extensively revised second edition offers a comprehensive exploration of TGA, providing a thorough understanding of its historical background, clinical manifestations, diagnostic criteria, and potential underlying mechanisms.

The book begins by delving into the historical aspects of TGA, tracing its origins and exploring the contributions of renowned researchers and clinicians who have made significant contributions to our understanding of this condition. This historical context sets the stage for the subsequent chapters, which delve into the clinical and diagnostic features of TGA.

The authors provide a detailed account of the clinical presentation of TGA, including the typical onset, duration, and severity of symptoms. They discuss the various types of TGA, such as spontaneous, provoked, and stress-related, and highlight the distinguishing characteristics that help differentiate these subtypes. The authors also provide a comprehensive overview of the diagnostic process, including the use of clinical interviews, cognitive tests, and neuroimaging techniques to establish a diagnosis.

In addition to the clinical aspects, the book explores the investigation and predisposing and precipitating factors for TGA. The authors discuss the role of stress, medication, medical conditions, and genetic predisposition in the development of TGA. They also explore the potential environmental factors that may contribute to the occurrence of TGA, such as alcohol consumption, head trauma, and infections.

To synthesise the diverse information presented in the book, the authors attempt to formulate ideas about the pathogenesis of TGA. They propose various theories and models that aim to explain the mechanisms underlying the occurrence of TGA. These theories encompass the role of stress, the activation of specific brain regions, and the involvement of neurotransmitters and immune systems.

Each chapter of the book is devoted to a practical and structured overview of a particular topic related to TGA. The authors use case studies to illustrate the material, providing real-world examples that help clinicians understand the clinical presentation and management of TGA. These case studies are accompanied by detailed discussions and analysis, allowing clinicians to apply the knowledge gained from the book to their own practice.

Transient Global Amnesia is an invaluable resource for any clinician with an interest in, or who encounters patients with, acute amnesia. Neurologists, general physicians, old age psychiatrists, geriatricians, clinical neuropsychologists, and primary care physicians, as well as other professions allied to medicine with similar interests, such as members of memory assessment teams, will find this book particularly useful. The comprehensive nature of the coverage and the use of case studies make it accessible to a wide range of medical backgrounds, ensuring that clinicians can gain a deep understanding of TGA and apply this knowledge to their practice.

In conclusion, this extensively revised second edition of Transient Global Amnesia provides a comprehensive and up-to-date overview of this intriguing neurological condition. By delving into the history, clinical features, diagnostic criteria, investigation, and pathogenesis of TGA, the book offers valuable insights for clinicians from a broad range of medical backgrounds. The use of case studies and practical discussions makes the material accessible and applicable, ensuring that clinicians can effectively manage and understand patients with TGA.

Weight: 314g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030989415
Edition number: 2nd ed. 2022

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