Translational Autoimmunity: Autoimmune Disease Associated with Different Clinical Features

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings explores autoimmunity and associated conditions, including aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. It discusses how the immune system distinguishes self from no self, works in infections, and elicits auto-reactive states and self-antigens.

Format: Paperback / softback
Length: 406 pages
Publication date: 01 April 2022
Publisher: Elsevier Science & Technology

Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings delves into the intricate realm of autoimmunity, exploring its connections with various clinical conditions. This comprehensive text addresses a wide range of topics, including aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. It provides a thorough examination of the immune system's mechanisms for self-recognition and self-tolerance, its role in infections, and the processes that lead to the development of auto-reactive states and self-antigens observed in autoimmune conditions.

Following this foundational overview, the book delves into the genetic and clinical aspects of the diverse spectrum of autoimmune diseases. These diseases are categorized into two main types: organ-specific autoimmune diseases and non-organ-specific autoimmune diseases, also referred to as systemic autoimmune diseases. Organ-specific autoimmune diseases target specific organs or tissues, while non-organ-specific autoimmune diseases affect multiple systems throughout the body.

Each chapter in Translational Autoimmunity offers a detailed exploration of these clinical settings, providing a comprehensive understanding of the immune system's role in these diseases. The text is enriched with illustrative examples, clinical case studies, and relevant research findings, making it accessible to both professionals and students in the field of immunology and medicine.

By unraveling the complexities of translational autoimmunity, this book sheds light on the potential for targeted therapies and personalized medicine in the treatment of autoimmune diseases. It serves as a valuable resource for researchers, clinicians, and healthcare practitioners seeking to advance our understanding and management of these complex conditions.

Dimension: 235 x 191 (mm)
ISBN-13: 9780323854153