Vascular Tissue Engineering: Methods and Protocols

The book explores the latest techniques used to study tissue engineered vascular grafts (TEVGs), including deriving vascular cells from monocytes and induced pluripotent stem cells, engineering vascular grafts using biomaterials and stem cells, biomaterial modification by anticoagulation molecules, 3D bioprinting, and fabrication of TEVGs with different geometry and multiphase structures. It also features protocols for grafting and evaluating vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability.

Format: Paperback / softback
Length: 262 pages
Publication date: 02 October 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into the most recent techniques employed in the study of tissue engineered vascular grafts (TEVGs). The chapters within this book encompass a diverse range of topics, including the derivation of vascular cells from monocytes and induced pluripotent stem cells; the engineering of vascular grafts utilizing various biomaterials and stem cells, including stem cell-derived or primary vascular cells; the modification of biomaterials through the incorporation of anticoagulation molecules; innovative vascular bioengineering technologies such as 3D bioprinting; and the fabrication of TEVGs with distinct geometries and multiphase structures. Furthermore, this book offers protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the renowned Methods in Molecular Biology series format, each chapter includes an introduction to its respective topic, a comprehensive list of the necessary materials and reagents, detailed step-by-step, readily reproducible laboratory protocols, and helpful tips on troubleshooting and avoiding known pitfalls.

Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, physicians, and nurses, as it provides cutting-edge and practical insights into the field of TEVGs. By exploring these advanced techniques, researchers and practitioners can further advance the development of effective and durable vascular grafts for medical applications.

Weight: 529g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071617106
Edition number: 1st ed. 2022