Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology

Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology explores the toxicokinetic and toxicodynamic,toxicogenomic,biotransformation,and resistance mechanisms of xenobiotics in carcinogenesis,and discusses major environmental xenobiotics and their risks,toxic xenobiotics,and their routes of exposure. It also highlights current achievements in predicting carcinogenicity and developing anticancer drugs.

Format: Paperback / softback
Length: 328 pages
Publication date: 01 March 2022
Publisher: Elsevier Science & Technology

Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology delves into the intricate realm of translational toxicology, exploring the mechanisms of xenobiotic substances in carcinogenesis. This comprehensive book provides a comprehensive overview of toxicokinetic and toxicodynamic processes, toxicogenomic insights, biotransformation mechanisms, and resistance pathways within the human body. It begins with a historical review, establishing a foundation for understanding the evolution and future prospects of chemical carcinogenesis.

The book then delves into the diverse world of environmental xenobiotics, shedding light on their potential risks in causing cancer. It explores the various routes of exposure to toxic xenobiotics in humans, emphasizing the role of xenobiotic metabolism in carcinogenesis. Furthermore, it delves into the toxicokinetic and toxicodynamic processes that underpin the development of cancer from xenobiotic exposure.

To augment the understanding of carcinogenic risks, the book explores the application of toxicogenomics, a powerful tool for predicting the carcinogenicity of xenobiotic substances. It discusses the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants.

In conclusion, Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology serves as a vital resource for researchers, scientists, and healthcare professionals seeking to unravel the complexities of xenobiotic-induced carcinogenesis. By providing a comprehensive exploration of toxicokinetic and toxicodynamic processes, toxicogenomic insights, biotransformation mechanisms, and resistance pathways, this book empowers readers to gain a deeper understanding of the mechanisms underlying cancer development and explore innovative approaches for cancer prevention, diagnosis, and treatment.

Weight: 450g
Dimension: 235 x 191 (mm)
ISBN-13: 9780323905602