Advances in Immunopharmacology

The latest release in the Advances in Pharmacology series, Volume 91, covers topics such as Modulation of inflammation and immune response by Nrf2, Therapeutic modulation of macrophage phenotype, Immodulation by cannabinoids, and The use of nanomaterials to target immunity. It also discusses Next generation in cancer immunotherapy, checkpoint inhibitors, Vaccines as a therapy for food allergy, Role of inflammation/immune system in depression, and Therapeutic targeting of tumor-associated macrophages, Mast cells, and more.

Format: Hardback
Length: 348 pages
Publication date: 09 June 2021
Publisher: Elsevier Science Publishing Co Inc

The ninth volume of Advances in Pharmacology, a highly regarded series, has been published, offering the most recent advancements in the field. This latest edition includes comprehensive chapters on various topics, such as:

Modulation of Inflammation and Immune Response by the Stress-Activated Transcription Factor Nrf2:
This chapter explores the role of the stress-activated transcription factor Nrf2 in regulating inflammation and immune responses. It discusses the mechanisms by which Nrf2 activates immune cells and promotes their anti-inflammatory activities. The chapter also highlights the potential therapeutic applications of Nrf2 in the treatment of inflammatory disorders.

Therapeutic Modulation of Macrophage Phenotype to Treat Acute and Chronic Liver Diseases:
Macrophages play a crucial role in the pathogenesis of liver diseases, including hepatitis, cirrhosis, and liver cancer. This chapter discusses the therapeutic modulation of macrophage phenotype to treat these diseases. It explores the use of various agents, such as drugs, cytokines, and nanoparticles, to alter macrophage behavior and promote tissue repair.

Immodulation by Cannabinoids:
Cannabinoids, the active components of cannabis, have been shown to have anti-inflammatory and immunomodulatory properties. This chapter discusses the use of cannabinoids as a potential therapy for a wide range of diseases, including chronic pain, inflammation, and cancer. It explores the mechanisms by which cannabinoids modulate immune cells and their potential benefits in treating immune-related disorders.

The Use of Nanomaterials to Target Immunity:
Nanomaterials, such as nanoparticles and liposomes, have the potential to enhance immune responses and target immune cells. This chapter discusses the use of nanomaterials in vaccine development, drug delivery, and immunotherapy. It explores the mechanisms by which nanomaterials modulate immune cells and their potential applications in the treatment of immune-related diseases.

Next Generation in Cancer Immunotherapy:
Cancer immunotherapy has emerged as a promising treatment approach for cancer patients. This chapter discusses the latest developments in cancer immunotherapy, including checkpoint inhibitors, vaccines, and adoptive cell therapy. It explores the mechanisms by which these therapies modulate immune cells and their potential benefits in treating cancer.

Checkpoint Inhibitors:
Checkpoint inhibitors are a class of drugs that block the immune system's checkpoints, allowing immune cells to attack cancer cells. This chapter discusses the use of checkpoint inhibitors in the treatment of various types of cancer, including lung cancer, melanoma, and renal cell cancer. It explores the mechanisms by which checkpoint inhibitors modulate immune cells and their potential benefits in treating cancer.

Vaccines as a Therapy for Food Allergy:
Food allergies are a growing concern worldwide. This chapter discusses the use of vaccines as a potential therapy for food allergies. It explores the mechanisms by which vaccines modulate immune cells and their potential benefits in preventing food allergies.

Role of Inflammation/Immune System in Depression:
Depression is a complex mental disorder characterized by inflammation and immune system dysregulation. This chapter discusses the role of inflammation/immune system in depression and the potential therapeutic applications of immune-modulating therapies in treating depression.

Therapeutic Targeting of Tumor-Associated Macrophages:
Macrophages are a critical component of the tumor microenvironment, promoting tumor growth and metastasis. This chapter discusses the therapeutic targeting of tumor-associated macrophages as a potential treatment strategy for cancer. It explores the use of various agents, such as drugs, cytokines, and nanoparticles, to alter macrophage behavior and promote tumor regression.

Mast Cells:
Mast cells are a type of immune cell that play a crucial role in the allergic response and inflammation. This chapter discusses the role of mast cells in the pathogenesis of autoimmune diseases and the potential therapeutic applications of mast cell inhibitors in treating these diseases.

In conclusion, Advances in Pharmacology, Volume 91, provides a comprehensive and up-to-date overview of the latest advancements in the field of pharmacology. The chapters cover a wide range of topics, from the modulation of inflammation and immune response to the therapeutic modulation of macrophage phenotype, the use of nanomaterials to target immunity, and the next generation in cancer immunotherapy. The book is an invaluable resource for researchers, physicians, and students interested in the field of pharmacology and immunology.

Weight: 660g
Dimension: 229 x 152 (mm)
ISBN-13: 9780128235621