Amino Acids: Insights and Roles in Heterocyclic Chemistry: Volume 4: Azlactones and Oxazolidin-5-ones

This first-of-its-kind four-volume book series provides comprehensive information on α-amino acids, including their potential challenges, protecting groups, and popular heterocyclic compounds derived from them. Volume 4: Azlactones and Oxazolidin-5-ones discusses these heterocycles' biological activities and synthetic methods. The other volumes cover protecting groups, hydantoins, thiohydantoins, 2,5-diketopiperazines, N-carboxyanhydrides, N-thiocarboxyanhydrides, sydnones, sydnonimines, azlactones, pseudoazlactones, and oxazolidin-5-ones. The set is valuable for graduate students, senior students, professors, and researchers in medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, and proteins and peptides.

Format: Hardback
Length: 416 pages
Publication date: 26 May 2023
Publisher: Apple Academic Press Inc.

This groundbreaking four-volume book series offers comprehensive and up-to-date information on α-amino acids, delving into the potential challenges associated with their utilization, the protective groups employed for the carboxyl and side chain groups, and the diverse heterocyclic compounds derived from α-amino acids. These heterocyclic compounds encompass a wide range of structures, including hydantoins, thiohydantoins (including 2-thiohydantoins, 4-thiohydantoins, 2,4-dithiohydantoins), 2,5-diketopiperazines, N-carboxyanhydrides, N-thiocarboxyanhydrides, sydnones, sydnonimines, azlactones, pseudoazlactones, and oxazolidin-5-ones. This comprehensive resource stands as the first to present a comprehensive overview of all the heterocycles that can be directly synthesized from α-amino acids. Furthermore, the series includes detailed mechanistic discussions and experimental procedures for almost all types of synthetic methods employed for a specific category of heterocycles derived from α-amino acids.

Volume 4: Azlactones and Oxazolidin-5-ones focuses specifically on two types of simple heterocycles that can be synthesized from α-amino acids: azlactones (also referred to as oxazolones, including 4-unsaturated azlactones) and oxazolidin-5-ones. These heterocyclic compounds exhibit distinct biological and chemical properties, and their biological activities are presented in a well-organized manner within this volume.

The remaining three volumes in the set are:

Volume 1: Protecting Groups
Volume 2: Hydantoins, Thiohydantoins, and 2,5-Diketopiperazines
Volume 3: N-Carboxyanhydrides, N-Thiocarboxyanhydrides, and Sydnones

Together, this exceptional 4-volume set provides a thorough and meticulously compiled exploration of the two types of heterocyclic compounds originating from α-amino acids. The author has generously shared numerous insightful perspectives based on their extensive expertise, making this resource an invaluable resource for researchers and practitioners in the field.

Weight: 970g
Dimension: 234 x 156 (mm)
ISBN-13: 9781774911587