Biology of Vascular Smooth Muscle: Vasoconstriction and Dilatation

This book provides a comprehensive review of vascular smooth muscle properties, regulation, and signaling, with a focus on new discoveries in vasoactive agents, enzymes, and transduction mechanisms. It covers cerebral, coronary, and pulmonary circulation, as well as vascular activity under hypoxia and aging. The second edition updates the first edition with the latest advances in vascular activity regulation from biochemical, structural, genetic, physiological, and pharmacological perspectives. Two new chapters on microRNA and extracellular vesicles are added to reflect their important roles in vascular activities.

Format: Hardback
Length: 424 pages
Publication date: 09 December 2022
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the intricate world of vascular smooth muscle, encompassing its morphological, biochemical, electrical, mechanical, and metabolic properties. It provides a thorough review of the regulation of vascular activities and the intracellular signaling mechanisms involved. With a particular focus on newly identified vasoactive agents, enzymes, and transduction mechanisms, the book explores the latest advancements in understanding the regulation of cerebral, coronary, and pulmonary circulation, as well as vascular activity under hypoxia and aging.

The second edition of this text aims to update the contents of the first edition by incorporating the latest achievements in the regulation of vascular activities from various biochemical, structural, genetic, physiological, and pharmacological perspectives. In addition, two new chapters have been added to highlight the newly discovered roles of microRNA and extracellular vesicles in vascular activities.

The contraction and dilatation activities of vasculature are crucial for maintaining circulation homeostasis and responding to physiological changes. Over the past four decades, significant progress has been made in unraveling the complex mechanisms that govern vascular activity. These insights into the responsiveness of blood vessels under normal and pathophysiological conditions offer invaluable tools in the fight against vascular diseases.

The book appeals to researchers and graduate students in the field of vascular biology, providing a valuable resource for advancing their understanding of this vital aspect of human health. Its comprehensive coverage and up-to-date information make it an essential reference for scholars and practitioners alike.

Weight: 822g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811971211
Edition number: 2nd ed. 2022