Biomembranomics: Structure, Techniques, and Applications

The membrane is a vital component of cells that performs numerous biological functions. However, research on membranes is still lacking, especially in comparison to genomics, proteomics, and metabolomics. This book introduces the concept of "biomembranomics" and compiles the latest advancements in structural analysis techniques for biomembranes. It provides a comprehensive understanding of biomembrane organization at the single-molecule level and offers valuable insights into the relationship between membrane structure and function.

Format: Unspecified
Length: 514 pages
Publication date: 23 November 2023
Publisher: Jenny Stanford Publishing

The membrane, a complex and vital component of living organisms, serves a multitude of essential biological functions. It plays a crucial role in the transport of materials, the transmission of signals, the transfer of energy, and the facilitation of enzymatic reactions. It is remarkable that the abnormal expression and distribution of certain membrane proteins can be linked to genetic disorders, neurodegenerative diseases, and even malignant tumors. Despite the immense importance of membranes, comprehensive and systematic research on membranes, akin to genomics, proteomics, and metabolomics, remains relatively limited. Moreover, the broad concept of biomembranes extends beyond the plasma membrane to include organelle membranes and membranes of endocytosis or exocytosis vesicles, all of which are derived from the biomembrane system.

In recognition of the need for a deeper understanding of biomembranes, this book introduces the concept of "omics" to membranes and proposes the term "biomembranomics." It serves as a comprehensive resource that compiles the latest advancements in structural analysis techniques for biomembranes. These techniques include single-molecule manipulation techniques, single-molecule fluorescence techniques, super-resolution fluorescence imaging, cryo-electron microscopy, mass spectrometry, molecular dynamics simulation, and hyphenated instrumental techniques. The book presents these methods in both text and illustrative formats, making it an invaluable and practical reference for researchers across various fields.

By delving into the intricacies of biomembrane organization at the single-molecule level, this book offers a profound understanding of the relationship between membrane structure and function. It provides valuable insights into the mechanisms underlying cellular processes, such as membrane fusion, protein trafficking, and signal transduction. Furthermore, the book opens up new avenues for exploring therapeutics and developing innovative approaches to address diseases associated with membrane dysfunction.

In conclusion, this book is a crucial resource for researchers, scientists, and students interested in biomembranes and their diverse functions. It offers a comprehensive and up-to-date perspective on structural analysis techniques for biomembranes, providing valuable insights into the relationship between membrane structure and function. With its practical and accessible nature, this book is essential reading for anyone seeking to advance their knowledge in this field.

Weight: 1150g
Dimension: 229 x 152 (mm)
ISBN-13: 9789814968614