Breast Cancer: From Bench to Personalized Medicine

This book provides comprehensive information on breast cancer, covering epidemiology, risk factors, diagnosis, prognosis, and treatment strategies. It discusses the association of breast cancer with other hormone-sensitive cancers, BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression, and noninvasive biomarkers for early detection. It also explores epigenetic modifications, non-coding RNAs, fibrinolytic mechanisms, circulating tumor cells, and oral PARP inhibitors as therapeutic targets. The book offers potential new options for personalized therapies for breast cancer patients.

Format: Hardback
Length: 536 pages
Publication date: 15 May 2022
Publisher: Springer Verlag, Singapore

This comprehensive book delves into the intricate details of breast cancer, encompassing its etiology, pathogenesis, diagnosis, prognosis, and treatment strategies. The first section of the book provides a comprehensive overview of epidemiology, risk factors, histopathological characteristics, immunohistochemistry, and molecular subtypes of breast cancer. It explores the association between breast cancer and other hormone-sensitive cancers, shedding light on the underlying mechanisms and implications.

The second section delves into the realm of BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression, and noninvasive biomarkers for the early detection of breast cancer. It discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis, highlighting their potential as biomarkers and therapeutic targets. The book also explores the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment.

In addition, it provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors as a treatment option for breast cancer. Furthermore, the book offers promising new avenues for personalized therapies in breast cancer, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.

By comprehensively covering these topics, this book serves as a valuable resource for healthcare professionals, researchers, and patients alike, empowering them with the knowledge and tools necessary to combat breast cancer effectively.

Weight: 992g
Dimension: 235 x 155 (mm)
ISBN-13: 9789811901966
Edition number: 1st ed. 2022