Cancer Stem Cells: Basic Concept and Therapeutic Implications

The book provides a comprehensive review of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to therapies, covering methods, detection, characterization, epigenetic pathways, metabolism, tumor heterogeneity, and immunotherapeutic approaches. It offers valuable insights into CSC biology and its therapeutic implications.

Format: Hardback
Length: 372 pages
Publication date: 27 July 2023
Publisher: Springer Verlag, Singapore

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Cancer stem cells (CSCs) play a crucial role in cancer initiation, progression, and resistance to anticancer therapies. This book provides a comprehensive review of the methods and procedures for detecting, isolating, and characterizing CSCs, as well as the epigenetic pathways that contribute to cancer initiation and tumorigenesis. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity in cancer biology. Additionally, it highlights the implications of CSCs on tumor heterogeneity and the therapeutic response. Towards the end, the book highlights the different immunotherapeutic approaches targeting CSCs with the potential of improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.

Dimension: 235 x 155 (mm)
ISBN-13: 9789819931842
Edition number: 1st ed. 2023