Cardiac Regeneration: Methods and Protocols

Cardiac Regeneration: Methods and Protocols is a comprehensive book that discusses techniques for replenishing lost cardiomyocytes, avoiding scar-associated pathology, and improving myocardial infarction outcomes. It is written for the highly successful Methods in Molecular Biology series and includes introductions, lists of materials and reagents, step-by-step laboratory protocols, and troubleshooting tips.

Format: Paperback / softback
Length: 346 pages
Publication date: 04 March 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive book delves into critical objectives of regenerative medicine and the cardiovascular research community, offering innovative techniques to replenish lost cardiomyocytes, mitigate scar-associated pathology, and enhance myocardial infarction (MI) outcomes. The collection commences with a section on cardiac injury models, encompassing zebrafish, neonatal and adult mice, and pigs, and proceeds with chapters dedicated to culturing cardiomyocytes from diverse species, as well as methods for labeling or manipulating cardiac tissue to address regeneration-related inquiries. Authored for the esteemed Methods in Molecular Biology series, the chapters feature introductions to their respective topics, comprehensive lists of the necessary materials and reagents, meticulously detailed step-by-step laboratory protocols, and valuable tips on troubleshooting and avoiding known pitfalls.

Cardiac Regeneration: Methods and Protocols stands as an authoritative and practical resource, presenting the most recent models and methods employed in the field of heart regeneration. Designed for researchers seeking to establish these assays in their laboratories to reproduce or extend findings, as well as for individuals seeking to familiarize themselves with the field if it is new to them, this book serves as a valuable tool for advancing knowledge and understanding in this rapidly evolving area.

One notable chapter, titled "Ventricular Cryoinjury as a Model to Study Heart Regeneration in Zebrafish," is available open access under a Creative Commons Attribution 4.0 International License via the link: link.springer.com. This chapter provides valuable insights into the use of zebrafish as a model system for studying heart regeneration, offering a comprehensive overview of the techniques and protocols employed to induce ventricular cryoinjury and examine the subsequent regenerative response.

In conclusion, this comprehensive book offers a wealth of knowledge and practical insights into cardiac regeneration, making it an essential resource for researchers, clinicians, and students interested in this field. By presenting the latest models and methods, it empowers individuals to advance their understanding of heart repair and regeneration, paving the way for new therapeutic approaches and improved patient outcomes.

Weight: 692g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071606704
Edition number: 1st ed. 2021