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Cell Polarity Signaling: Methods and Protocols

Cell Polarity Signaling: Methods and Protocols

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  • More about Cell Polarity Signaling: Methods and Protocols

This volume explores detailed methods to investigate various aspects of biology related to cell polarity,or asymmetry within a cell. It includes advanced imaging and biochemical methods,planar cell polarity (PCP) signaling in morphogenesis,apicobasal (AB) cell polarity in development and diseases,and directional cell migration and biomechanics. Written for the highly successful Methods in Molecular Biology format,chapters include introductions,lists of materials and reagents,step-by-step protocols,and tips on troubleshooting.

Format: Paperback / softback
Length: 530 pages
Publication date: 11 February 2022
Publisher: Springer-Verlag New York Inc.


This comprehensive volume delves into intricate methods to explore diverse aspects of biology related to cell polarity, also known as asymmetry within a cell. It encompasses molecular, cellular, and tissue-level regulation and function, as well as diseases caused by impairment of cell polarity. The book begins with advanced imaging and biochemical techniques and proceeds to discuss planar cell polarity (PCP) signaling in morphogenesis across various developmental contexts. It also explores apicobasal (AB) cell polarity in development and diseases, as well as directional cell migration and biomechanics in cell polarity.

The collection includes the utilization of a wide range of model systems and an extensive array of techniques, including genetic, imaging, biochemical, and biomechanical approaches. Written in the highly successful Methods in Molecular Biology format, chapters feature introductions to their respective topics, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and comprehensive, Cell Polarity Signaling: Methods and Protocols aims to empower researchers to delve into the captivating field of cell polarity and contribute to our understanding of how coordinated control of protein stability, trafficking, membrane retention, post-translational modification, and dynamic organization leads to active regulation of cell polarity.

Chapter 29 is available open access under a Creative Commons Attribution 4.0 International License via the link: link.springer.com.

Weight: 1023g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071620373
Edition number: 1st ed. 2022

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