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Joanna Moncrieff

Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth

Chemically Imbalanced: The Making and Unmaking of the Serotonin Myth

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Featured on ITV’s THIS MORNING and in SUNDAY TIMES MAGAZINE

'controversial and courageous' – DAILY MAIL

For years, we’ve been led to believe that depression is caused by a chemical imbalance in the brain and antidepressants are the solution. But what if this widely accepted belief has been built on unreliable truths?

In Chemically Imbalanced, renowned psychiatrist Joanna Moncrieff takes readers on a thought-provoking journey through the history of the serotonin theory of depression, from its origins in the 1960s to its widespread acceptance in the 1990s. With clarity and compelling evidence, Moncrieff exposes how scientific understanding has been swayed by social and economic forces, leading to misconceptions that have shaped treatment decisions for millions.

Accessible yet profoundly insightful, Chemically Imbalanced is essential reading for anyone seeking to make more informed choices about their mental health and understand the forces that shape the way we perceive and treat depression today.

  • Publication date: 3 September 2026
  • Dimensions: Height 198 mm; Width 129 mm
  • Publisher: The History Press Ltd
  • Format: Paperback
  • ISBN-13: 9781837052677

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