Chiral Intermediates and Chiral Drugs

Chirality is essential in the pharmaceutical industry, with one enantiomer of hyoscyamine possessing greater pharmacological activity than the other. Regulatory agencies are reviewing the importance of chirality with regard to pharmaceutical and agrochemical products, leading to the focus on single enantiomer products. Chiral Intermediates and Chiral Drugs provide comprehensive listings of chiral chemicals and drugs, with specific data of interest for each entry.

Format: Hardback
Publication date: 01 January 2021
Publisher: Taylor & Francis Ltd

This title, originally published in 2001, played a pivotal role in highlighting the significance of chirality in the pharmaceutical industry during the early 20th century. It was discovered that one enantiomer of hyoscyamine exhibited greater pharmacological activity than its counterpart, leading to a growing recognition of chirality's importance in drug development. Fast forward to the present day, and the vast majority of new drugs and those in development consist of a single optically active isomer, underscoring the continued relevance of chirality. Moreover, chirality has become a significant concern for the agrochemical and other industries, prompting regulatory agencies worldwide to reassess its importance in pharmaceutical and agrochemical products. New guidelines from these agencies have been instrumental in driving the focus towards single enantiomer products in these sectors. This has created a need for a comprehensive guide that provides workers in the pharmaceutical and chemical industries with information on chiral molecules, processes, and commercially available chiral chemicals. Enter Chiral Intermediates, a groundbreaking resource that offers a comprehensive listing of over 4700 available chiral chemicals, each accompanied by detailed data of interest. Its companion volume, Chiral Drugs, follows a similar format, presenting comprehensive information for over 2000 chiral drugs. Together, these volumes serve as invaluable tools for professionals seeking to gain a deeper understanding of chirality and its applications in the pharmaceutical and chemical industries.

ISBN-13: 9781138703902