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Chromosome Architecture: Methods and Protocols
Chromosome Architecture: Methods and Protocols
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- More about Chromosome Architecture: Methods and Protocols
This new edition of Chromosome Architecture: Methods and Protocols provides cutting-edge laboratory protocols, techniques, and applications in use by international experts in the field. It emphasizes the increasing physiological relevance of chromosome architecture investigation, with applications in vitro and in living, functional cells. The book covers single-molecule approaches, advanced computational methods, and mathematical analysis, making it an ideal guide for researchers working in this dynamic area.
Format: Hardback
Length: 330 pages
Publication date: 31 May 2022
Publisher: Springer-Verlag New York Inc.
This comprehensive new edition brings together cutting-edge laboratory protocols, techniques, and applications employed by some of the foremost international experts in the expansive field of chromosome architecture. The book underscores the growing physiological significance of studying chromosome architecture, evident through the application of more intricate bottom-up assays in vitro and the preservation of the native physiological context through the investigation of living, functional cells. Furthermore, the chapters showcase the remarkable advancement in precision achieved through single-molecule approaches, encompassing imaging of chromosome DNA content and proteins that bind to DNA, as well as methods that enable controllable manipulation of individual DNA molecules. Additionally, advanced computational methods and mathematical analysis are prominently featured. Authored for the highly acclaimed Methods in Molecular Biology series, the chapters encompass introductions to their respective topics, comprehensive lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and valuable tips on troubleshooting and avoiding known pitfalls. Thorough and up-to-date, Chromosome Architecture: Methods and Protocols, Second Edition serves as an invaluable guide for researchers engaged in this dynamic and rapidly evolving field of study.
Weight: 845g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071622209
Edition number: 2nd ed. 2022
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