Clinical Neuroembryology: Development and Developmental Disorders of the Human Central Nervous System

This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischaemic causes. It is intended for advanced medical students and clinicians working with children and adults with developmental disorders of the CNS.

Format: Hardback
Length: 916 pages
Publication date: 12 September 2023
Publisher: Springer International Publishing AG

This comprehensive book delves into the intricate development of the human central nervous system (CNS), exploring its diverse range of developmental disorders stemming from genetic, environmental, and hypoxic/ischaemic factors. Presented in three introductory chapters, it provides a broad overview of the evolution of the human brain and spinal cord, highlights the mechanisms of development observed in various invertebrates and vertebrates, and explores the causes of congenital malformations.

The subsequent chapters delve into the regional and segmental developmental disorders of the human brain and spinal cord, commencing with neurulation and neural tube defects and culminating in developmental disorders of the cerebral cortex. These chapters are visually captivating, featuring abundant color illustrations accompanied by carefully selected clinical case studies enriched with imaging data, whenever available, and postmortem verification of the developmental disorders involved.

In the third edition, particular emphasis has been placed on developmental ontology, employing the prosomeric approach, and fetal development. Updates have been made to prenatal diagnosis techniques, including ultrasound, MRI, and DTI, and classifications of developmental disorders have been revised. Additionally, a host of new clinical cases have been included, showcasing the practical applications of the knowledge presented.

This book is specifically designed for advanced medical students and clinicians specializing in the field of developmental disorders of the CNS. Its unique strength lies in its seamless integration of data from human embryology, experimental and molecular findings in mice, particularly in imaging and developmental neuropathology. By bridging these diverse disciplines, the book offers a comprehensive and multidisciplinary perspective on the study and understanding of CNS development and its associated disorders.

Weight: 2769g
Dimension: 279 x 210 (mm)
ISBN-13: 9783031260971
Edition number: 3rd ed. 2023