Computational Systems Biology in Medicine and Biotechnology: Methods and Protocols

This book provides state-of-the-art systems biology-oriented approaches to tackle complex questions in medicine and biotechnology. It is organized into six parts and includes methodological approaches applied at different levels, from molecular to organismal. Each chapter is written in the Methods in Molecular Biology series format and includes case studies, tutorials, and tips on troubleshooting. The goal is to excite experts and stimulate newcomers to the field.

Format: Hardback
Length: 493 pages
Publication date: 24 May 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into the latest state-of-the-art systems biology-oriented approaches employed by Computational Systems Biology, an interdisciplinary field that seamlessly integrates experimental tools with computational tools to address complex questions at the forefront of knowledge in medicine and biotechnology. The chapters in this book are organized into six distinct parts: systems biology of the genome, epigenome, and redox proteome; metabolic networks; aging and longevity; systems biology of diseases; spatiotemporal patterns of rhythms, morphogenesis, and complex dynamics; and genome-scale metabolic modeling in biotechnology.

In each chapter, readers will encounter a diverse range of methodological approaches applied at various levels, spanning from molecular, cellular, organ, to organismal, genomic, and phenotypic dimensions. Written in the highly successful Methods in Molecular Biology series format, chapters feature comprehensive introductions to their respective topics, outlining the criteria employed for utilizing specific methodologies. They provide comprehensive lists of the necessary materials, reagents, software, databases, algorithms, mathematical models, and dedicated analytical procedures, all presented in a didactic and clear style, accompanied by abundant illustrations, including express case studies and tutorials. Additionally, chapters offer valuable tips on troubleshooting and advice for achieving reproducibility while avoiding mistakes and misinterpretations.

The overarching goal driving this volume is to ignite the expertise of seasoned professionals and inspire newcomers to the field of Computational Systems Biology. By presenting cutting-edge and authoritative insights, Computational Systems Biology in Medicine and Biotechnology: Methods and Protocols serves as a valuable resource for pre- and post-graduate students, researchers, and practitioners alike, facilitating their understanding and exploration of this rapidly evolving field.

Weight: 1150g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071618301
Edition number: 1st ed. 2022