Design and Development of Novel Drugs and Vaccines: Principles and Protocols

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols provides in silico and experimental methods for vaccine and drug design and development, critically reviewing current research and emphasizing approaches and technologies that accelerate and lower the cost of product development.

\n Format: Paperback / softback
\n Length: 308 pages
\n Publication date: 22 January 2021
\n Publisher: Elsevier Science Publishing Co Inc
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The Design and Development of Novel Drugs and Vaccines: Principles and Protocols is a comprehensive resource that provides both in silico methods and experimental protocols for vaccine and drug design and development. It critically reviews the most current research in this field, emphasizing approaches and technologies that accelerate and lower the cost of product development. The book is organized into several sections, each covering a different aspect of drug and vaccine design and development.

The first section explores the technologies and approaches used to identify, characterize, and establish a protein as a new drug and vaccine target. It discusses the use of various molecular methods, such as genomics, proteomics, and bioinformatics, to analyze the structure, function, and interactions of proteins. The section also covers several molecular methods for in vitro studies of the desired target, including cell culture, molecular biology techniques, and biochemical assays.

The second section focuses on physiological parameters for in vivo studies. It discusses the use of animal models, such as mice, rats, and non-human primates, to evaluate the safety and efficacy of drugs and vaccines. The section also covers various experimental protocols, such as pharmacokinetic and pharmacodynamic studies, toxicology studies, and clinical trials.

The third section of the book includes preclinical trials and research. It provides information on the design and execution of preclinical studies, including dose-finding studies, safety studies, and efficacy studies. The section also discusses the regulatory requirements for drug and vaccine development, including FDA approval.

Overall, The Design and Development of Novel Drugs and Vaccines: Principles and Protocols is an essential resource for researchers, scientists, and healthcare professionals involved in vaccine and drug design and development. It provides a comprehensive overview of the current research and technologies in this field, and emphasizes the importance of interdisciplinary collaboration and innovative approaches to accelerate the development of safe and effective treatments.

\n Weight: 490g\n
Dimension: 152 x 229 x 22 (mm)\n
ISBN-13: 9780128214718\n \n