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DNA Modification Detection Methods
DNA Modification Detection Methods
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- More about DNA Modification Detection Methods
The accurate detection, quantification, and mapping of DNA modifications are essential for understanding their functional roles. This book provides a comprehensive overview of available techniques and methods for analyzing various types of DNA modifications, including 5mC, 5hmC, 5fC, 5caC, 5hmU, 5fU, 6mA, base J, and 8-oxo-7,8-dihydroguanine. It is a valuable resource for biochemists and molecular biologists interested in investigating DNA modifications.
Format: Paperback / softback
Length: 194 pages
Publication date: 07 July 2022
Publisher: Springer-Verlag New York Inc.
Understanding the functional roles of DNA modifications requires accurate detection, quantification, and mapping of these modifications. Over the past few years, significant advancements in methods for deciphering DNA modifications have revolutionized the field of epigenetics. In addition to DNA cytosine methylation (5-methylcytosine, 5mC), the best-characterized epigenetic modification, numerous novel modifications have been discovered in DNA.
This comprehensive book provides a detailed overview of available techniques and methods, along with comprehensive step-by-step protocols, for conducting analysis on various types of DNA modifications, including 5mC, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), 5-carboxycytosine (5caC), 5-hydroxymethyluracil (5hmU), 5-formyluracil (5fU), N6-methyladenine (6mA), β-D-glucosyl-5-hydroxymethyluracil (base J), and 8-oxo-7,8-dihydroguanine (OG). This laboratory manual serves as a valuable resource for biochemists and molecular biologists from diverse fields interested in investigating DNA modifications.
Weight: 390g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071612316
Edition number: 1st ed. 2022
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