Endotoxin Induced-Shock: a Multidisciplinary Approach in Critical Care

This book provides easy consultation and guidance for an appropriate understanding and management of endotoxic shock, which results from a severe, generalized inflammatory response induced by bloodstream infection with gram-negative bacteria. It is structured focusing on antibiotics, corticosteroids, volume support, vasoactive and cardiostimulating drug, coagulopathy and nutritional support, and includes updated tips related to the diagnosis and management of endotoxic shock with a multidisciplinary approach. It is addressed to healthcare providers working in intensive care and represents a point of reference for intensivists, infectious disease physicians, nephrologists, and critical care nurses.

Format: Hardback
Length: 133 pages
Publication date: 13 January 2023
Publisher: Springer International Publishing AG

This comprehensive book offers invaluable guidance and consultation for a proper understanding and management of endotoxic shock, a severe condition resulting from a widespread inflammatory response triggered by bloodstream infection with gram-negative bacteria. While gram-negative bacteria are the primary culprits behind endotoxic shock, it's important to note that other factors, such as Gram-Positive and yeast infections, can also disconnect the endotoxin-induced inflammatory activation. Additionally, this condition can occur in various clinical scenarios, including post-cardiac arrest syndrome and trauma, possibly due to gut barrier dysfunction and subsequent endotoxin translocation.

The clinical management of endotoxic shock is meticulously structured, with dedicated chapters covering antibiotics, corticosteroids, volume support, vasoactive and cardiostimulating drugs, coagulopathy, and nutritional support. Furthermore, this book stands out for its detailed explanation of polymixin b hemoperfusion, highlighting molecular interactions and hydrodynamics of sorption. Each section in the book includes:

• A brief overview of pathophysiology
• Principles of management
• Key messages

For readers seeking the most up-to-date tips related to the diagnosis and management of endotoxic shock, this book offers a multidisciplinary approach. It provides a clear pathway from the structure and source of endotoxin to the underlying pathophysiology of endotoxic shock, emphasizing the specific clinical aspects and focusing on medical clinical management of endotoxemia and extracorporeal removal. Authored by esteemed international opinion leaders in this field, the book is tailored to healthcare providers working in intensive care settings. It serves as a valuable reference for intensivists, infectious disease physicians, nephrologists, and critical care nurses who are actively involved in the management of endotoxic shock.

In addition to its comprehensive content, the book is enriched with useful downloadable material, making it an invaluable resource for practitioners in the field. Whether you're a seasoned healthcare professional or a student seeking to expand your knowledge in this area, this book is an essential tool for achieving excellence in the management of endotoxic shock.

Weight: 415g
Dimension: 235 x 155 (mm)
ISBN-13: 9783031185908
Edition number: 1st ed. 2023