Epigenetics in Organ Specific Disorders

Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation in different organ types and organ-specific disorders, exploring the role of epigenetic mechanisms in stem cells, cell-matrix interactions, cell proliferation, migration, apoptosis, necrosis, pyknosis, tumor suppression, and immune responses. It also discusses the use of epigenetic mechanisms and biomarkers in developing precision therapies that can selectively target the organ of interest.

Format: Paperback / softback
Length: 666 pages
Publication date: 05 December 2022
Publisher: Elsevier Science Publishing Co Inc

A groundbreaking new addition to the Translational Epigenetics series, "Epigenetics in Organ Specific Disorders" delves into the intricate world of epigenetic gene regulation, offering a comprehensive and nuanced exploration of this field. Providing a foundational overview, the book goes beyond mere definitions and delves into the specific mechanisms that govern epigenetic processes in different organ types and organ-specific disorders.

Chapter authors begin by comparing epigenetic regulations across normal and disease conditions in various organ tissues, highlighting both similarities and differences. This comparative analysis sheds light on the underlying mechanisms that contribute to disease development and provides valuable insights into potential therapeutic targets.

The book then delves into the role of epigenetic mechanisms in stem cells, cell-matrix interactions, cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types. By examining these critical processes, the book offers a deeper understanding of the complex interplay between epigenetics and organ function.

Furthermore, the book explores the potential of organ-specific epigenetic mechanisms and biomarkers as early indicators of disease and as tools for developing targeted therapies. By selectively targeting the organ of interest, these precision therapies have the potential to revolutionize the treatment of various diseases, including cancer and neurological disorders.

In conclusion, "Epigenetics in Organ Specific Disorders" is a vital resource for researchers, clinicians, and students interested in epigenetics and its implications for human health. With its comprehensive coverage, insightful analysis, and practical applications, this book serves as a cornerstone for understanding the complex interplay between epigenetics and organ function and paving the way for new precision therapies in the future.

Weight: 1330g
Dimension: 192 x 236 x 36 (mm)
ISBN-13: 9780128239315