Flow and Microreactor Technology in Medicinal Chemistry

The ability to synthesize new drug-like compounds with the push of a button is the ultimate dream for medicinal chemists. Recent developments in computer-controlled automated syntheses using miniature flow reactors provide a workable technology for synthesizing new chemical substances quickly and with minimal effort. This book introduces current and emerging uses for automated synthesis in a drug discovery context, with numerous case studies and how-to guides for integrating flow synthesis with drug discovery.

Format: Hardback
Length: 368 pages
Publication date: 27 July 2022
Publisher: Wiley-VCH Verlag GmbH

The ultimate aspiration of medicinal chemists is to develop the capability to rapidly synthesize novel drug-like compounds with the mere press of a button. The fundamental secret to expediting and enhancing the accuracy of chemical compound synthesis lies in the utilization of computer-controlled technologies that can be further optimized through machine learning. Recent advancements in computer-controlled automated syntheses, facilitated by miniature flow reactors equipped with integrated analysis of the generated products, offer a practical solution for swiftly generating new chemical substances with minimal effort.

In "Flow and Microreactor Technology in Medicinal Chemistry," pioneering practitioners of this groundbreaking technology provide an in-depth exploration of its current and potential applications within the realm of medicinal chemistry. Drawing upon successful examples of the utilization of flow and microreactor synthesis for drug-like compounds, the book introduces both established and emerging applications of automated synthesis in the context of drug discovery.

For readers of "Flow and Microreactor Technology in Medicinal Chemistry," a wealth of valuable insights and practical guidance is offered. Numerous case studies are presented, offering detailed accounts of the most prevalent applications of this technology in the daily operations of medicinal chemists. Furthermore, the book provides comprehensive instructions on how to seamlessly integrate flow synthesis with drug discovery processes, as well as on how to execute enantioselective reactions under continuous flow conditions.

"Flow and Microreactor Technology in Medicinal Chemistry" serves as an indispensable practical reference for medicinal chemists, organic chemists, and natural products chemists, irrespective of their affiliation with academia or the pharmaceutical industry. By delving into the realm of flow and microreactor technology, this book empowers professionals to unlock new avenues for drug discovery and innovation, propelling the field forward into a future of unparalleled potential and advancements.

Weight: 890g
Dimension: 254 x 174 x 23 (mm)
ISBN-13: 9783527346899