Flow Chemistry in Drug Discovery
Flow Chemistry in Drug Discovery
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This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, offering a reference tool for medicinal chemists interested in synthesizing biologically active compounds. It covers fundamental methodologies, non-conventional activation techniques, process development, automatization, and library synthesis. It also discusses how flow chemistry contributes to drug discovery R&D in developing countries and its green character.
Format: Paperback / softback
Length: 479 pages
Publication date: 09 December 2022
Publisher: Springer Nature Switzerland AG
This comprehensive book delves into the intricate challenges and remarkable opportunities presented by flow chemistry in drug discovery, serving as a valuable reference tool for medicinal chemists passionate about the synthesis of biologically active compounds. Compiled by esteemed experts, the chapters within this publication encompass a wide range of topics, including fundamental methodologies and reactions such as catalysis, particularly biocatalysis and organocatalysis, as well as non-conventional activation techniques spanning from photochemistry to electrochemistry. Moreover, the book explores the development of novel process windows, processes, and reactions in drug synthesis, with a special emphasis on automatization and library synthesis, which hold immense significance in the pharmaceutical industry. Additionally, readers will find valuable insights into selected topics of general interest, such as the role of flow chemistry in advancing drug discovery R&D in developing countries and its environmentally friendly nature, particularly in the production of raw materials for the pharmaceutical industry from waste.
With its extensive coverage, this book appeals to medicinal chemistry researchers, both in academia and industry, as well as professionals engaged in scale-up and drug development. It serves as a vital resource for anyone seeking to stay at the forefront of this rapidly evolving field and harness the power of flow chemistry to unlock new medicinal possibilities.
Weight: 771g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030855949
Edition number: 1st ed. 2021
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