Fundamentals of Molecular Bioengineering

This textbook provides a comprehensive introduction to molecular bioengineering, covering the molecular thermodynamics of biological systems and computational aspects of protein structure prediction and molecular dynamics. It is suitable for courses in molecular biophysics, biochemistry, physical chemistry, and bioengineering, and appeals to researchers and professionals in these fields.

Format: Hardback
Length: 272 pages
Publication date: 05 December 2023
Publisher: Springer International Publishing AG

This comprehensive textbook delves into the intricate realm of molecular bioengineering, a groundbreaking field that seamlessly blends technology, biology, and chemistry. It serves as a vital resource for students seeking to gain a deeper understanding of molecular mechanisms beyond the confines of biological phenomena. The textbook is meticulously organized into two parts, each dedicated to exploring different aspects of biomolecular machinery.

In Part I, the focus lies on the molecular thermodynamics of biological systems. Here, students are introduced to fundamental concepts such as thermodynamics and statistical mechanics, which form the foundation for comprehending how molecular properties manifest in macroscopic phenomena. The chapter also provides an insightful introduction to proteins, delving into topics such as intermolecular forces, volumetric properties of fluids, ionization equilibria, salting-out, protein binding, and protein-protein interactions.

Part II of the textbook takes students on a journey into the realm of protein structure prediction and analysis. It explores cutting-edge computational tools and approaches that enable scientists to unravel the intricate structures of proteins. The chapter also delves into systems biology and structure-based protein networks, providing valuable insights into how proteins interact and collaborate within biological systems. Additionally, students will gain practical knowledge about computational methods for molecular dynamics simulations and protein binding and protein-protein interactions, which are crucial for understanding the dynamic behavior of biomolecules.

What sets this textbook apart is its unique contribution to the scholarly discourse in the field of biophysical chemistry and molecular biophysics. It addresses important emerging areas that are not extensively covered in existing textbooks, making it an invaluable resource for courses in molecular biophysics, biochemistry, physical chemistry, and bioengineering. Moreover, the textbook's broad scope appeals to researchers and professionals alike, as it provides a comprehensive overview of the latest advancements and developments in this rapidly evolving field.

Part I of this book is particularly noteworthy as it underwent a remarkable transformation through the collaborative efforts of artificial intelligence and human revision. The initial manuscript was expertly translated from its Italian original, and then subjected to a rigorous human revision process. This meticulous approach ensures that the content is accurate, comprehensive, and accessible to a wide audience.

In conclusion, this textbook is a must-have for anyone seeking to delve into the world of molecular bioengineering. Its comprehensive coverage, coupled with its unique approach, makes it an invaluable resource for students, researchers, and professionals alike. By providing a deep understanding of biomolecular machinery and its role in various biological processes, this textbook empowers individuals to contribute to the ongoing advancements in this field and drive innovation in healthcare, biotechnology, and other scientific disciplines.

Dimension: 235 x 155 (mm)
ISBN-13: 9783031420214
Edition number: 1st ed. 2023