Terry A. Brown
Genomes 5
Genomes 5
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Genomes 5 is a comprehensive and up-to-date textbook on genomes and their investigation, covering techniques, genome anatomies, functions, evolution, and applications in various organisms. It includes revised coverage of genome sequencing and assembly methods, genome annotation, expression, replication, and evolution. The book is organized into four parts and features superb artwork, short-answer questions, and in-depth problems to test readers' understanding. It is ideal for upper-level courses focused on genomes and genomics.
Format: Hardback
Length: 548 pages
Publication date: 28 April 2023
Publisher: Taylor & Francis Ltd
Genomes 5 has undergone a complete revision and update, making it a thoroughly modern textbook on genomes and their investigation. This textbook follows a consistent structure, beginning with techniques, followed by genome anatomies, genome functions, and finally genome evolution. As with previous editions, the focus is on techniques, with genome anatomies and genome functions taking center stage.
The scope of Genomes 5 is vast, covering the genomes of all types of organisms, including viruses, bacteria, fungi, plants, and animals, including humans and other hominids. The book emphasizes the importance of understanding the genomes of different organisms in fields such as medicine, agriculture, and biotechnology.
Genome sequencing and assembly methods have been extensively revised to incorporate the latest developments in long-read DNA sequencing. Coverage of genome annotation emphasizes genome-wide RNA mapping, including CRISPR-Cas 9 and GWAS methods for determining gene function. The knowledge gained from these techniques forms the basis of the chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements).
Genome expression and replication are approached from a genomic perspective, focusing on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Examples of the applications of metabolomics and systems biology are also included to provide a comprehensive understanding of genomics.
The final chapter of Genomes 5 explores genome evolution, including the evolution of the epigenome, the study of human evolution using genomics, and the use of population genomics in plant breeding. Established methods of molecular biology are included, with explanations as to why they are still relevant today.
Genomes 5 is designed to be a highly accessible and well-structured textbook, with chapters organized into four parts to aid navigation. The book features superb artwork that enhances the understanding of complex genomic concepts.
In conclusion, Genomes 5 is an essential resource for upper-level courses focused on genomes and genomics. With its comprehensive coverage, up-to-date information, and accessible writing style, it is an invaluable tool for students, researchers, and professionals in the field.
Dimension: 280 x 210 (mm)
ISBN-13: 9780367678661
Edition number: 5 ed
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