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VeliMakinen,Djamal, Algiers) Belazzougui,FabioCunial,Alexandru I.Tomescu

Genome-Scale Algorithm Design: Bioinformatics in the Era of High-Throughput Sequencing

Genome-Scale Algorithm Design: Bioinformatics in the Era of High-Throughput Sequencing

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  • More about Genome-Scale Algorithm Design: Bioinformatics in the Era of High-Throughput Sequencing

This book provides a comprehensive algorithmic toolkit for bioinformatics, covering sequence analysis, index structures, graph algorithms, network flows, and advanced omics applications. It includes examples, visualizations, and exercises and is accompanied by a website with teaching material. The second edition strengthens the toolkit with minimizers and other advanced data structures.

Format: Hardback
Length: 487 pages
Publication date: 12 October 2023
Publisher: Cambridge University Press


This comprehensive textbook delves into the core algorithms and data structures that drive bioinformatics workflows, encompassing a wide array of topics from the fundamentals of sequence analysis to advanced omics applications. It begins by exploring the foundations of sequence analysis, including alignments and hidden Markov models, and then moves on to cover classical index structures such as k-mer indexes, suffix arrays, and suffix trees. The book also discusses Burrows–Wheeler indexes, graph algorithms, network flows, and a variety of cutting-edge omics applications. Each chapter is accompanied by numerous examples, algorithm visualizations, and exercises, making it an invaluable resource for graduate students, researchers, and practitioners in the field. Furthermore, an accompanying website (www.genome-scale.info) provides supplementary teaching material to enhance the learning experience. In the second edition, the toolkit is further strengthened by introducing minimizers and other advanced data structures, highlighting their applications in emerging pangenomics approaches. By presenting a comprehensive and up-to-date coverage of these essential algorithms and data structures, this textbook equips readers with a powerful algorithmic toolkit to tackle the challenges of high-throughput sequencing and advance their understanding of biological systems.

Weight: 974g
Dimension: 177 x 253 x 33 (mm)
ISBN-13: 9781009341233
Edition number: 2 Revised edition

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