Genomic Surveillance and Pandemic Preparedness

Genomic Surveillance and Pandemic Preparedness provides practical instruction in genomic surveillance, drawing from the COVID-19 pandemic. It covers host and pathogen genome interaction, population-level prevalence, individual disease susceptibility, gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity.

Format: Paperback / softback
Length: 450 pages
Publication date: 01 July 2023
Publisher: Elsevier Science Publishing Co Inc

Genomic Surveillance and Pandemic Preparedness is a comprehensive guide that delves into the practical applications, strategies, and reasons for employing genomic surveillance in combating pandemics. Drawing extensively from the lessons learned during the COVID-19 pandemic, this book offers in-depth insights into various aspects of microbes, with a particular focus on viral genome sequencing and analysis, the implementation and interpretation of genomic surveillance, and best practices for global data sharing in future pandemic preparedness.

More than a dozen international authors, each with expertise in their respective fields, contribute to this book. They explore the intricate interplay between host and pathogen genomes, examine population-level prevalence, investigate individual disease susceptibility and gene protection, analyze pathogen mutation evolutionary dynamics, examine the role of RNA modulation in infection, explore pathogen diversity, and examine the impact of coinfections and comorbidities on disease severity.

A wide range of examples, spanning from bacterial pathogens to fungal and viral infections, with a strong emphasis on recent COVID-19 analysis, are presented throughout the book. These examples serve to illustrate the practical applications of genomic surveillance and its significance in pandemic preparedness.

Furthermore, the authors provide step-by-step guidance in experimental and computational approaches for genomic surveillance, encompassing nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout the book, emphasis is placed on inference, which is the process of moving from genomic sequencing to meaningful genomic surveillance that strengthens pandemic preparedness.

Genomic Surveillance and Pandemic Preparedness is an essential resource for researchers, healthcare professionals, policymakers, and anyone interested in understanding the role of genomic surveillance in pandemic prevention and response. By providing a comprehensive and up-to-date understanding of the field, this book contributes to the global effort to enhance preparedness and mitigate the impact of future pandemics.

Weight: 450g
Dimension: 235 x 191 (mm)
ISBN-13: 9780443187698