Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics

The Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics provides a comprehensive review of the anatomy, physiology, biochemistry, and pathology of the eye, with a focus on drug therapy, drug delivery, and the use of therapeutic medical miniature devices. It discusses the pharmacological actions of drugs acting on the eye, including the unique principles of drug delivery and access to the site of action. The book covers general principles of pharmacokinetics and pharmacodynamics, as well as the therapy of ocular disorders and diseases, including the ocular side effects of systemically administered drugs, drugs used in ophthalmic surgery, and miscellaneous agents. It also discusses the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy. The Handbook is useful as a primary and secondary source of reference for pharmacologists, pharmaceutical scientists, students in the health care disciplines, and practitioners in optometry and ophthalmology.

Format: Paperback / softback
Length: 420 pages
Publication date: 24 June 2022
Publisher: Elsevier Science Publishing Co Inc

The Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics is a comprehensive resource that delves into the intricate anatomy, physiology, biochemistry, and pathology of the eye, with a particular emphasis on drug therapy, drug delivery, and the utilization of therapeutic medical miniature devices. To gain a comprehensive understanding of the pharmacological actions of drugs that affect the eye, both students and healthcare practitioners must acquire additional principles from the fields of basic and clinical sciences that are specific to this organ. As a sensory organ, the eye is relatively inaccessible to the systemic circulation due to the blood-vitreous, blood-aqueous, and blood-retinal barriers. Consequently, the administration of drugs for therapeutic purposes in the eye requires a deep understanding of the physico-chemical properties of these molecules and the pharmacokinetic principles involved in their access to the site of action through topical, intracameral, and intravitreal administration.

This book offers valuable insights into the general principles of pharmacokinetics and pharmacodynamics as they pertain to the eye and the treatment of ocular disorders and diseases. Employing a disease-themed approach, the book comprehensively discusses the basic and clinical pharmacological principles involved in the therapy of various ocular conditions, including the ocular side effects of systemically administered drugs, drugs used in ophthalmic surgery, and miscellaneous agents. Additionally, it explores the therapeutic utility of biologics, drug conjugates, combination products, gene and cellular therapy, and other emerging therapeutic modalities.

The Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics serves as a valuable primary and secondary source of reference for pharmacologists, pharmaceutics, and other healthcare professionals seeking up-to-date information about the pharmacological mechanisms of action, pharmacokinetics, side effects, drug-drug interactions, and therapeutic indications of drugs for the eye. By comprehensively covering these topics, the book empowers practitioners to provide optimal care and treatment to patients with ocular disorders and diseases.

Dimension: 235 x 191 (mm)
ISBN-13: 9780128192917