Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives

The book discusses hematopoietic challenges in different and emerging ways, with chapters written by faculty and researchers from prestigious institutions. It offers a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs, and discusses the microenvironmental niche where stem cells exist and develop into distinct blood cell types. It also provides valuable information related to developments in hematopoiesis that will be helpful for understanding the basics of hematopoiesis and the clinical treatment of blood diseases.

Format: Hardback
Length: 288 pages
Publication date: 16 January 2024
Publisher: Apple Academic Press Inc.

This groundbreaking new volume delves into the intricate realm of hematopoietic challenges, offering fresh perspectives and innovative approaches to understanding these complex issues. Written by esteemed faculty and researchers from prestigious institutions, the book provides a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs. It presents cutting-edge concepts related to the regulation of hematopoietic stem cell development, survival, proliferation, and differentiation, as well as the microenvironmental niche where stem cells exist and develop into distinct blood cell types.

Furthermore, the book explores a model system used to study non-coding RNA functions and the transformation of normal cells into cancer cells. Key features of this invaluable resource include:

• A detailed exploration of the available investigative tools and techniques for isolating and studying single blood cells in different model systems.
• A comprehensive discussion of the epigenetics of hematopoiesis, shedding light on the mechanisms that control gene expression and cellular differentiation.
• A thoughtful consideration of the clinical outcomes of defective hematopoiesis, highlighting the importance of understanding these processes in the treatment of blood diseases.
• A detailed examination of hematopoiesis and cancer stem cells, providing insights into the mechanisms underlying the development and progression of cancer.
• A thorough exploration of hematopoiesis in relation to specific diseases, such as minimal residual disease (MRD) and leukemia, aiding in the development of targeted therapies.

Hematopoiesis: Biochemical, Cellular, Molecular, and Genomic Perspectives is a must-read for clinicians, medical school students, and researchers in hematology. It offers valuable insights into the latest developments in hematopoiesis, facilitating a deeper understanding of the fundamentals of hematopoiesis and the clinical treatment of blood diseases. With its comprehensive coverage and expert contributions, this book serves as a valuable resource for advancing our knowledge in this field.

Weight: 750g
Dimension: 234 x 156 (mm)
ISBN-13: 9781774914724