Introduction to Adaptive Trial Designs and Master Protocols

This guidebook provides an in-depth understanding of adaptive trial designs and master protocols, introducing innovative approaches such as adaptive trial designs, master protocols, platform trials, basket trials, and umbrella trial designs. It offers a revisionist history of clinical research, case-study-based discussions, and practical considerations from collective experience. With real-world examples from personalized medicine and high-profile diseases, it is the go-to resource for medical students and researchers working in clinical trial research.

Format: Paperback / softback
Length: 256 pages
Publication date: 06 April 2023
Publisher: Cambridge University Press

This comprehensive high-level guidebook provides an in-depth exploration of the rapidly evolving field of clinical trial designs, particularly focusing on adaptive trial designs and master protocols. Written in a concise and accessible manner, the book delves into the most innovative approaches in clinical trial research, including adaptive trial designs, master protocols, platform trials, basket trials, and umbrella trial designs. While avoiding technical jargon, it offers a clear and concise understanding of these complex concepts, making it suitable for both professionals and enthusiasts alike.

The book begins with a revisionist history of clinical research, tracing its evolution from traditional trial designs to the contemporary approaches employed today. It then moves on to a case-study-based discussion, highlighting the practical considerations and challenges associated with these novel designs. Through real-world examples from the recent developments in medical research efficiency driven by personalized medicine and high-profile diseases such as COVID-19 and cancer, readers gain a deeper understanding of the strengths and limitations of these innovative designs.

The book is uniquely positioned as the first of its kind, serving as a valuable resource for medical students and researchers engaged in clinical trial research. It offers a comprehensive overview of the field, covering key concepts, methodologies, and applications, enabling readers to stay up-to-date with the latest advancements and apply them to their individual areas of research and clinical practice.

In conclusion, this practical and informative guidebook is a must-read for anyone interested in clinical trial research. It provides a comprehensive understanding of the latest trends and innovations in clinical trial design, equipping readers with the knowledge and tools necessary to advance their understanding and contribute to the field.

Weight: 334g
Dimension: 157 x 235 x 12 (mm)
ISBN-13: 9781108926980