Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

Imaging mass spectrometry (MS) techniques are widely used but often without a deep understanding of their principles. This book provides a comprehensive guide to spatial mapping of biomolecules, covering ionization sources, sample preparation, visualization, identification, quantification, and data analysis. It also includes case studies on analyzing specific biomolecule classes, with illustrative figures and future directions.

Format: Paperback / softback
Length: 270 pages
Publication date: 29 April 2021
Publisher: Elsevier Science Publishing Co Inc

Imaging mass spectrometry (MS) techniques are frequently employed without a thorough comprehension of their underlying principles, which poses challenges for scientists in determining the appropriate timing and methodologies for utilizing MS to visualize their specific biomolecules of interest. To address this need, Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry serves as a valuable resource for scientists seeking to understand the current state and emerging strategies in biomolecule analysis. This comprehensive book explores the diverse applications of imaging MS across various classes of biomolecules, providing a solid foundation of knowledge in this field.

The book begins by introducing ionization sources, sample preparation techniques, visualization guidelines, molecule identification methods, quantification approaches, and data analysis methodologies. These foundational chapters serve as a roadmap for scientists to gain a deep understanding of imaging MS and its potential applications.

The second section of the book focuses on case studies that illustrate the practical application of imaging MS in analyzing specific biomolecule classes. Each case study includes an introduction that provides background information and context, followed by a summary of successful imaging MS studies that showcase the analysis of biomolecules using illustrative figures and future directions for research.

By providing a comprehensive and in-depth exploration of imaging MS techniques, Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry empowers scientists to leverage this powerful tool for visualizing and understanding biomolecules in a wide range of scientific disciplines. Whether they are newcomers to the field or experienced researchers seeking to advance their knowledge, this book serves as a valuable resource for anyone interested in exploring the spatial mapping of biomolecules.

Weight: 446g
Dimension: 154 x 227 x 16 (mm)
ISBN-13: 9780128189986