Melatonin: Methods and Protocols

Melatonin: Methods and Protocols is a comprehensive volume that covers the latest techniques in studying melatonin synthesis, receptor function, and cellular and systemic effects. It is organized into three parts and includes methods for detecting melatonin, manipulating its synthesis, measuring its biological effects, and exploring its physiological effects in animal models. Written in the Methods in Molecular Biology series format, the book is a valuable resource for researchers interested in investigating melatonin.

Format: Hardback
Length: 500 pages
Publication date: 01 October 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume delves into the latest techniques employed to study the synthesis, receptor function, and cellular and systemic effects of melatonin. Organized into three distinct parts, Part One explores the detection of melatonin and its biological derivatives in various biological samples, the manipulation of melatonin synthesis by the pineal gland in animals, and the primary source of melatonin in mammals. Part Two delves into methods to measure the biological effects and consequences of melatonin binding to high-affinity G protein-coupled receptors. Part Three focuses on measuring the physiological effects regulated by melatonin in animals, particularly in rodent models. Written in the renowned Methods in Molecular Biology series format, each chapter includes an introduction to the respective topic, a comprehensive list of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and valuable tips on troubleshooting and avoiding known pitfalls.

With its extensive coverage and detailed protocols, Melatonin: Methods and Protocols serves as an invaluable resource for researchers seeking to explore the multifaceted aspects of melatonin, from its production to its mechanisms of action and widespread systemic effects. Whether you are a novice or an experienced researcher, this book will provide you with the essential tools and knowledge to advance your understanding of this important hormone and its role in regulating sleep, metabolism, and immune function.

Weight: 1157g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071625927
Edition number: 1st ed. 2022