Metabotropic Glutamate Receptor Technologies

This volume highlights various techniques used to study multiple aspects of mGlu receptor function, including development and screening of allosteric modulators, intracellular calcium fluctuations, dopamine-glutamate interactions, localization, and modulation in behavior. It is a valuable resource for researchers in neuroscience and physiology.

Format: Paperback / softback
Length: 314 pages
Publication date: 12 February 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume explores diverse techniques employed to investigate multiple facets of mGlu receptor function. The chapters within this book delve into various topics, including contemporary strategies for designing and evaluating allosteric modulators, the dynamics of intracellular calcium fluctuations induced by mGlu receptor activation, the interplay between dopamine and glutamate in the central nervous system, methodologies for determining the localization of mGlu receptors, and commonly used approaches for assessing mGlu modulation in behavior in rodents, encompassing stress and alcohol consumption. In keeping with the Neuromethods series format, the chapters offer a wealth of detailed information and valuable insights from esteemed experts, equipping researchers with the necessary tools to achieve successful outcomes in their laboratory endeavors. With its cutting-edge and practical approach, Metabotropic Glutamate Receptor Technologies serves as a valuable resource for researchers engaged in the fields of neuroscience and physiology, particularly those focused on understanding the roles and implications of mGlu receptors in various peripheral systems.

Weight: 625g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071611098
Edition number: 1st ed. 2021