Microcephaly: Methods and Protocols

This volume discusses the latest imaging and molecular techniques for studying microcephaly through neural progenitor proliferation, survival, and gene expression, using the mouse as a model system. It includes cellular, metabolic, transcriptomic studies, MR imaging studies, and developmentally-adapted studies of behavior.

Format: Hardback
Length: 176 pages
Publication date: 24 November 2022
Publisher: Springer-Verlag New York Inc.

This comprehensive volume explores the latest imaging and molecular techniques for studying microcephaly, focusing on neural progenitor proliferation, survival, and gene expression. Employing the mouse as a model system, the book encompasses cellular, metabolic, transcriptomic studies of neural progenitors, as well as MR imaging studies of brain growth in three dimensions and developmentally-adapted studies of behavior in neonatal mice. Written in the renowned Methods in Molecular Biology series format, chapters include introductions to their respective topics, comprehensive lists of necessary materials and reagents, detailed step-by-step laboratory protocols, and helpful tips on troubleshooting and avoiding common pitfalls.

With its cutting-edge and comprehensive approach, Microcephaly: Methods and Protocols serves as an invaluable resource for researchers seeking to deepen their understanding of this crucial and rapidly evolving field. By providing a thorough exploration of the latest techniques and methodologies, this book empowers researchers to advance their knowledge and contribute to the ongoing research efforts aimed at mitigating the impact of microcephaly and promoting optimal brain development.

Weight: 562g
Dimension: 254 x 178 (mm)
ISBN-13: 9781071627518
Edition number: 1st ed. 2023