Modeling Inhibitors of Matrix Metalloproteinases

Matrix metalloproteinases (MMPs) are promising biomolecular targets for novel drug design and discovery against numerous major disease conditions. This book covers various modern molecular modeling methodologies for designing potential and target-specific or selective MMPIs, benefiting medicinal chemists and academia.

Format: Hardback
Length: 474 pages
Publication date: 29 December 2023
Publisher: Taylor & Francis Ltd

Matrix metalloproteinases (MMPs) have emerged as highly promising biomolecular targets for developing novel drugs and discovering treatments for a wide range of severe disease conditions, including various cancers, cardiovascular diseases, neurodegenerative disorders, and inflammatory diseases. This comprehensive book delves into diverse modern molecular modeling methodologies, specifically focusing on the design and discovery of MMP inhibitors. It provides detailed descriptions of ligand-based drug designing and structure-based drug designing modeling strategies, aimed at creating potential MMPIs with specific or selective properties. The book is invaluable for those seeking an in-depth understanding of the design and discovery processes of novel and selective MMPIs.

The book offers a comprehensive overview of modeling strategies applied to MMPs, providing a deep understanding of the structural and functional aspects of these enzymes. It elaborates on the designing strategies of MMPs, emphasizing their role in disease pathology and the development of targeted therapies. The book includes in-depth analyses of relevant case studies, showcasing the successful application of molecular modeling methodologies in the discovery and development of MMP inhibitors. It serves as a valuable resource for medicinal chemists, not only from pharmaceutical industries but also from academia, as it covers various modern molecular modeling methodologies, particularly related to MMPIs.

In conclusion, this book is a must-read for researchers, scientists, and medicinal chemists interested in exploring the potential of MMP inhibitors as therapeutic agents for a diverse range of diseases. It provides a comprehensive and up-to-date overview of modern molecular modeling methodologies, specifically tailored to the design and discovery of MMPIs. With its detailed descriptions, case studies, and practical insights, it serves as a valuable guide for those seeking to advance the field of drug discovery and development in the area of MMP inhibitors.

Weight: 1070g
Dimension: 234 x 156 (mm)
ISBN-13: 9781032289267