Molecular Diagnostics in Cytopathology: A Practical Handbook for the Practicing Pathologist

Molecular diagnostics are increasingly used to guide targeted therapy in solid organ tumors and hematologic malignancies. Cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. This proposed text will provide a user-friendly quick-reference handbook to serve as a useful resource for practicing pathologists and laboratory personnel dealing with and interested in this evolving field of molecular cytopathology.

Format: Paperback / softback
Length: 534 pages
Publication date: 17 December 2018
Publisher: Springer International Publishing AG

Molecular diagnostics play a crucial role in guiding targeted therapy for solid organ tumors and hematologic malignancies. A significant portion of molecular testing is conducted on limited-volume samples obtained through minimally invasive techniques like fine needle aspiration. Cytopathologists are essential in this process, both during rapid on-site evaluation and in evaluating archival samples for suitability for ancillary testing. As the landscape of known genomic alterations continues to evolve, it is imperative for practicing cytopathologists to stay abreast of the latest diagnostic, prognostic, and predictive ancillary tests that can be utilized on limited cytologic material.

This challenge is further compounded by the ever-expanding array of testing options. To address this, the proposed text will serve as a user-friendly quick-reference handbook for practicing pathologists and laboratory personnel dealing with, and interested in, this evolving field of molecular cytopathology. Key components to be covered include:

1. Pre-analytic factors that influence sample selection and evaluation.
2. Specimen preparation techniques to maximize confidence in results.
3. Interpretation of molecular testing results, including the use of molecular markers and genetic algorithms.
4. Potential limitations and challenges associated with molecular testing.
5. Workflow algorithms to streamline the process of molecular testing.

In addition, specific disease-specific molecular testing details will be outlined to provide the reader with resources for quick reference. All chapters will be written by experts in their respective fields and will incorporate the most up-to-date scientific and clinical information.

Molecular Diagnostics in Cytopathology will be of immense value to Cytopathologists, Cytotechnologists, Cytotechnology students, Cytopathology fellows, Surgical pathologists, Pathology residents, and researchers in the field of pathology. By providing a comprehensive and up-to-date resource, this handbook will help practitioners stay at the forefront of this rapidly advancing field and improve patient outcomes.

Weight: 656g
Dimension: 128 x 203 x 24 (mm)
ISBN-13: 9783319973968
Edition number: 1st ed. 2019