Multiple Sclerosis: Practical Comprehensive Essentials

Multiple sclerosis (MS) is a progressive neurological disease that affects millions of people worldwide. The causes of MS are still unclear, and the cure remains symptomatic. Immunopathogenesis of MS involves activation of peripheral leucocytes against putative CNS antigens, activated leucocytes with inflamed cerebral endothelial cells, the migration of activated lymphocytes and macrophages through the endothelium to the CNS environment, and further propagation of a massive immune response within the CNS. Genetic factors also play a central role in the development of MS. Axonal degeneration and neuronal loss are the core components of irreversible and permanent CNS atrophy and disability in MS. This book provides a comprehensive overview of the current MS situation as researchers try to understand the process and develop treatments that can slow or stop the disease, possibly repair the damage, alleviate specified symptoms, and improve the abilities of MS patients to function in everyday life. Various biological holistic approaches have been shown to slow disease progression in some patients, and the recovery rate of cellular mechanisms in the brain and spinal cord has been accelerated, increasing the possibility of achieving complete balance of the disease state.

Format: Paperback / softback
Length: 152 pages
Publication date: 28 June 2022
Publisher: Troubador Publishing

Multiple sclerosis (MS) is a progressive neurological disorder that impacts millions of individuals worldwide. While the exact causes of MS remain unknown, the disease primarily affects the central nervous system (CNS), encompassing the brain and spinal cord. The clinical manifestations and neurological deficits resulting from MS exhibit significant variability, as it can affect various levels of the CNS. The immunopathogenesis of MS involves intricate processes, including the activation of peripheral leucocytes against potential CNS antigens, the interaction between activated leucocytes and inflamed cerebral endothelial cells, the migration of activated lymphocytes and macrophages through the endothelium to the CNS environment, and the subsequent amplification of a robust immune response within the CNS. This extensive immune activation leads to the breakdown of the myelin-oligodendrocyte complex, a crucial component of the CNS. A multitude of immune cells and mediators contribute to the progression of MS, with genetic factors also playing a central role in the development of most forms of the disease. Axonal degeneration and neuronal loss are fundamental components of irreversible and permanent CNS atrophy and disability in MS.

In the face of this challenging condition, researchers are diligently striving to comprehend the underlying mechanisms of MS and develop effective treatments that can slow down or even halt the disease's progression. These treatments aim to repair damage, alleviate specific symptoms, and enhance the functional abilities of MS patients. Various biological holistic approaches have shown promising results in slowing down disease progression in certain individuals. Additionally, the recovery rate of cellular mechanisms in the brain and spinal cord has been accelerated, offering hope for improved outcomes.

This comprehensive book provides a thorough examination of the current MS landscape, highlighting the latest research and therapeutic advancements. It explores various aspects of MS, including its diagnosis, treatment options, and the impact on the lives of individuals affected by the disease. The book also discusses the role of genetics in MS development and the potential for personalized medicine approaches. By providing a comprehensive overview of MS, this resource aims to empower patients, healthcare professionals, and researchers with the knowledge and tools necessary to address this complex neurological disorder and improve the quality of life for those impacted by it.

Dimension: 254 x 203 (mm)
ISBN-13: 9781803131184