Nanoparticles in the Lung: Environmental Exposure and Drug Delivery

Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides insights into how inhaled nanoparticles behave in the human lungs and body, including deposition, interactions with the alveolar surface and epithelium, translocation across the air–blood tissue barrier, and accumulation in the body.

Format: Paperback / softback
Length: 404 pages
Publication date: 30 September 2020
Publisher: Taylor & Francis Ltd

Nanoparticles, with their physical dimensions comparable to molecular structures on the cell surface, exhibit distinct behavior when interacting with cells compared to larger particles. This unique behavior is attributed to their smaller size, which allows for more intimate interactions and potential effects on cellular processes. Understanding the behavior of nanoparticles in the lung is crucial, as they can be inhaled through the air and enter the bloodstream.

Nanoparticles in the Lung: Environmental Exposure and Drug Delivery, a comprehensive text authored by renowned subject-matter experts, delves into the intricate details of how inhaled nanoparticles behave within the human lungs and body. This authoritative work provides a detailed account of the sequence of events that nanoparticles encounter as they move from the air into the bloodstream. It encompasses deposition, interactions with the alveolar surface and epithelium, translocation across the air–blood tissue barrier, and accumulation in various organs.

In addition to these fundamental aspects, the book addresses practical considerations for drug delivery to the respiratory tract, including drug and gene delivery in the lungs, and the use of bio-nanocapsules. It explores the physicochemical, colloidal, and transport properties of nanoparticles, shedding light on their potential applications in various fields. Cutting-edge research on special issues such as dosimetry for in vitro nanotoxicology, nanoparticle deposition in the developing lungs, and the potential for nose-to-brain delivery of drugs is presented, highlighting the ongoing advancements in this field.

The significance of Nanoparticles in the Lung: Environmental Exposure and Drug Delivery lies in its ability to offer the most updated and comprehensive knowledge regarding the risks and benefits associated with nanoparticle inhalation. By providing a deep understanding of the behavior of nanoparticles in the lung, this book aims to protect humans from any harmful effects and explore the potential utility of nanoparticles as drug delivery carriers. It serves as a valuable resource for researchers, healthcare professionals, policymakers, and individuals interested in understanding the implications of nanoparticle exposure and its potential applications in medicine.

Weight: 744g
Dimension: 254 x 178 (mm)
ISBN-13: 9781138749207