Nanotherapeutics: From Laboratory to Clinic

Nanotherapeutics is a new approach to treating critical human diseases that combines nanotechnology,recombinant DNA technology,and synthetic organic chemistry with medicine. It discusses the current shortcomings for delivering classical drugs and vaccines and the use of synthetic/chemical engineering methods and recombinant,hybridoma,and phage display technologies to fabricate nanoparticulate carriers and drugs. It also covers the preclinical and clinical trials of potential nanoparticle-based products in animal models and patients and the approval/commercialization of nanotherapeutics.

Format: Paperback / softback
Length: 356 pages
Publication date: 13 June 2022
Publisher: Taylor & Francis Ltd

Nanotherapeutics, a groundbreaking field of medicine, has emerged as a result of the seamless integration of nanotechnology, recombinant DNA technology, and synthetic organic chemistry. By employing a more precise and targeted molecular approach, nanotherapeutics aims to effectively treat critical human diseases, surpassing the limitations of conventional drug therapy.

In this comprehensive text, Nanotherapeutics: From Laboratory to Clinic delves into the challenges faced in delivering classical (small) drugs, macromolecular therapeutics, and recombinant vaccines through conventional intravascular and extravascular routes. The book explores innovative synthetic/chemical engineering methods, recombinant, hybridoma, and phage display technologies, which are employed to fabricate diverse types of nanoparticulate carriers and drugs. It also sheds light on the various approaches taken by harnessing nanotechnology to overcome multistep extracellular and intracellular barriers, paving the way for the development of novel strategies for therapeutic delivery and imaging.

The author delves into the preclinical and clinical trials of potential nanoparticle-based products in animal models and patients, highlighting the approval/commercialization of nanotherapeutics for various human diseases. A unique feature of this book is its focus on bridging the gap between laboratory findings, which originate from research on identifying cellular and systemic barriers of classical and macromolecular drugs, and clinical outcomes, which result from testing selected potential nanotherapeutics on patients suffering from specific diseases.

Furthermore, Nanotherapeutics: From Laboratory to Clinic fills a gap in the existing literature by providing a comprehensive overview of the design and development of diversified nanotherapeutics. This book serves as a valuable resource for researchers, medical professionals, and students interested in advancing the field of nanomedicine and improving patient outcomes.

Dimension: 234 x 156 (mm)
ISBN-13: 9781032339993