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Walter A.Orenstein,Paul A., MDOffit,Kathryn M.Edwards,Stanley A. Plotkin

Plotkin's Vaccines

Plotkin's Vaccines

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Plotkin's Vaccines, 8th Edition, is an award-winning text that provides reliable information on vaccination from global authorities. It covers every aspect of vaccination, including new vaccine development, and the use of vaccines in reducing disease. The book has been completely revised and updated, with new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines. It also includes updated content on new vaccine technologies, such as mRNA vaccines, and emerging vaccines. The book provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use. It also covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. The enhanced eBook version includes access to all of the text, figures, and references from the book on a variety of devices.

Format: Hardback
Length: 1808 pages
Publication date: 05 May 2023
Publisher: Elsevier - Health Sciences Division


From the latest vaccination evidence, recommendations, and protocols to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as an indispensable guide to the enhancement of the well-being of our world, Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field.

Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality.

Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration.

This comprehensive textbook is an essential resource for healthcare professionals, researchers, and students interested in vaccines and immunology. It provides a thorough and up-to-date overview of the field, covering the history, science, and clinical applications of vaccines, as well as the latest developments in vaccine research and development.

The book is organized into nine chapters, each covering a different aspect of vaccination. The first chapter provides an introduction to vaccines and their history, including the development of the first vaccines and the role of vaccines in eradicating infectious diseases. The second chapter discusses the basic principles of vaccine development, including the identification of vaccine candidates, the production of vaccines, and the evaluation of vaccine efficacy and safety.

The third chapter explores the different types of vaccines available, including live attenuated vaccines, inactivated vaccines, subunit vaccines, and conjugate vaccines. The fourth chapter focuses on the immune response to vaccines, including the mechanisms of immunity and the factors that influence vaccine efficacy. The fifth chapter discusses the use of vaccines in preventing infectious diseases, including the prevention of measles, mumps, rubella, polio, and other vaccine-preventable diseases.

The sixth chapter explores the use of vaccines in reducing the risk of non-infectious diseases, such as cancer and cardiovascular disease. The seventh chapter discusses the challenges and controversies surrounding vaccination, including vaccine hesitancy and vaccine safety concerns. The eighth chapter discusses the role of vaccines in global health, including the development of vaccines for emerging diseases and the use of vaccines in low- and middle-income countries.

The ninth chapter provides a comprehensive review of the latest vaccination evidence, recommendations, and protocols, including the use of vaccines in the COVID-19 pandemic.

Throughout the book, Plotkin emphasizes the importance of vaccination in improving public health and reducing the burden of infectious and non-infectious diseases. He provides a wealth of information on the benefits and risks of vaccination, as well as the strategies that can be used to promote vaccination and increase vaccine coverage.

Plotkin's Vaccines is an authoritative and comprehensive textbook that is essential for anyone interested in vaccines and immunology. It is written in a clear and accessible style, making it suitable for students, healthcare professionals, and researchers alike. The book is well-referenced and up-to-date, with a wealth of information and insights that will help readers stay informed about the latest developments in the field.

In conclusion, Plotkin's Vaccines, 8th Edition, is an indispensable resource for anyone interested in vaccines and immunology. It provides a thorough and up-to-date overview of the field, covering the history, science, and clinical applications of vaccines, as well as the latest developments in vaccine research and development. The book is well-referenced and up-to-date, with a wealth of information and insights that will help readers stay informed about the latest developments in the field. Whether you are a healthcare professional, researcher, or student, this textbook is a must-have for anyone interested in vaccines and immunology.

Weight: 3866g
Dimension: 224 x 285 x 67 (mm)
ISBN-13: 9780323790581
Edition number: 8 ed

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