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Post-Transplant Lymphoproliferative Disorders

Post-Transplant Lymphoproliferative Disorders

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  • More about Post-Transplant Lymphoproliferative Disorders


Post-Transplant Lymphoproliferative Disorders 2nd Edition is a comprehensive guide to the diagnosis and treatment of post-transplant lymphoproliferative disorders,with updated information on new classifications,treatment paradigms,and diagnostic techniques. It is designed to be a valuable reference for oncologists and all transplant professionals.

Format: Paperback / softback
Length: 314 pages
Publication date: 12 February 2022
Publisher: Springer Nature Switzerland AG


Post-Transplant Lymphoproliferative Disorders (PTLD) is a complex disorder that spans multiple disciplines and requires a collaborative approach to enhance knowledge and treatment. This second edition, authored by highly experienced and internationally recognized experts, has undergone a thorough update, incorporating numerous new chapters, including those focused on genetic abnormalities observed in PTLDs. In this successor edition, a dedicated section has been dedicated to Post-Transplant Lymphoproliferative Disorders (PTLDs) after hematopoietic stem cell transplantation. The book incorporates the latest PTLD classifications and treatment paradigms, reflecting the results of recent international trials. As technologies continue to advance, this book offers state-of-the-art diagnostic and prognostic insights, providing valuable guidance to oncologists, transplant professionals, and trainees alike.

The multidisciplinary nature of PTLD necessitates a team-based approach to ensure optimal care for transplant patients. This edition includes contributions from a diverse group of experts, ensuring a comprehensive coverage of the topic. The book begins with an introduction to the pathogenesis and clinical presentation of PTLD, providing a foundation for subsequent chapters.

The authors then delve into the diagnostic evaluation of PTLD, discussing the importance of histopathology, immunohistochemistry, and molecular techniques in confirming the diagnosis. They provide detailed descriptions of the various subtypes of PTLD, including Epstein-Barr virus-associated lymphoproliferative disorders, T-cell lymphoproliferative disorders, and B-cell lymphoproliferative disorders. Each subtype is discussed in detail, including its clinical features, treatment options, and outcomes.

The management of PTLD is a multifaceted endeavor, and the book provides comprehensive guidance on various treatment modalities. The authors discuss the role of chemotherapy, radiation therapy, immunotherapy, and targeted therapy in the treatment of PTLD. They also explore the use of stem cell transplantation as a potential treatment option, particularly in cases of advanced or refractory disease.

In addition to treatment strategies, the book emphasizes the importance of surveillance and follow-up for PTLD patients. The authors discuss the frequency of surveillance examinations, the appropriate diagnostic tests, and the management of complications associated with PTLD. They also provide insights into the long-term outcomes and quality of life for patients with PTLD.

Post-Transplant Lymphoproliferative Disorders 2nd Edition is an invaluable resource for oncologists, transplant professionals, and trainees alike. It provides comprehensive and up-to-date information on the diagnosis, treatment, and management of PTLD. The book's multidisciplinary approach and expert contributions make it an essential tool for improving the care and outcomes of transplant patients with PTLD.

Weight: 504g
Dimension: 235 x 155 (mm)
ISBN-13: 9783030654054
Edition number: 2nd ed. 2021

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