Principles of Cancer Genetics

Principles of Cancer Genetics provides a theoretical framework for understanding why cancers arise, how they develop, and how they can be treated. It focuses on the genes and signaling pathways involved in the most common tumors and introduces the concepts of T cell activation, immunoediting, and immune evasion. It is a useful resource for laypersons, students, and researchers with a general interest in cancer.

Format: Hardback
Length: 431 pages
Publication date: 26 June 2022
Publisher: Springer Nature Switzerland AG

This comprehensive textbook, now in its third edition, offers a theoretical framework for comprehending the origins, development, and treatment of cancer. It provides a detailed exploration of the factors that contribute to cancer formation, the mechanisms by which it progresses, and the various approaches employed for its management.

Special emphasis is placed on understanding the evolutionary aspects of cancer, emphasizing how mutant cell populations tend to expand and disseminate. By focusing on the genes and signaling pathways involved in the most prevalent tumors, Principles of Cancer Genetics presents a highly accessible account that will appeal to individuals seeking a fundamental understanding of cancer biology. This book is particularly valuable for students who have completed introductory courses in genetics, biology, and biochemistry, as well as medical students and medical house staff who are embarking on their journey into the complex realm of cancer research and treatment.

In its updated edition, this textbook delves into the critical interplay between growing tumors and the immune system. It introduces concepts such as T cell activation, immunoediting, and immune evasion, which play pivotal roles in cancer progression and response to therapy. Furthermore, the book provides comprehensive descriptions of novel strategies for cancer diagnosis and prognosis, encompassing the roles of next-generation sequencing and liquid biopsies. Established and emerging therapeutic modalities are extensively discussed, offering a detailed account of the latest advancements in cancer care.

Designed to be accessible to a broad audience, including laypersons, students, and researchers with a general interest in cancer, this book is enriched with numerous easy-to-understand illustrations. It serves as a valuable resource for those seeking an introductory overview of the field, while also providing advanced students considering future study in oncology and cancer research with a concise guide to the fundamental principles that underpin our understanding of cancer.

Weight: 968g
Dimension: 161 x 242 x 27 (mm)
ISBN-13: 9783030993863
Edition number: 3rd ed. 2022